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CAZyme Information: MGYG000003248_00153
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS1004 sp900761685 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; Borkfalkiaceae; UMGS1004; UMGS1004 sp900761685 | |||||||||||
| CAZyme ID | MGYG000003248_00153 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | DNA mismatch repair protein MutS | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 189831; End: 201251 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG4646 | COG4646 | 4.09e-82 | 1203 | 1732 | 1 | 540 | Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]. |
| pfam12960 | DUF3849 | 3.51e-37 | 2963 | 3087 | 1 | 124 | Protein of unknown function (DUF3849). A family of uncharacterized proteins found by clustering human gut metagenomic sequences. This domain frequently seen with DUF3848. |
| COG4646 | COG4646 | 2.88e-27 | 1863 | 2066 | 427 | 637 | Adenine-specific DNA methylase, N12 class [Replication, recombination and repair]. |
| pfam01624 | MutS_I | 1.76e-22 | 264 | 338 | 2 | 76 | MutS domain I. This domain is found in proteins of the MutS family (DNA mismatch repair proteins) and is found associated with pfam00488, pfam05188, pfam05192 and pfam05190. The MutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair; other members of the family included the eukaryotic MSH 1,2,3, 4,5 and 6 proteins. These have various roles in DNA repair and recombination. Human MSH has been implicated in non-polyposis colorectal carcinoma (HNPCC) and is a mismatch binding protein. The aligned region corresponds with globular domain I, which is involved in DNA binding, in Thermus aquaticus MutS as characterized in. |
| PRK05399 | PRK05399 | 2.56e-22 | 262 | 338 | 8 | 84 | DNA mismatch repair protein MutS; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ASV45029.1 | 4.52e-298 | 908 | 2428 | 1553 | 3142 |
| QIW86704.1 | 9.40e-297 | 908 | 2488 | 1621 | 3256 |
| QIW86628.1 | 9.40e-297 | 908 | 2488 | 1621 | 3256 |
| AXF51455.1 | 3.68e-279 | 913 | 2486 | 1792 | 3436 |
| AEY69616.1 | 4.23e-277 | 913 | 2486 | 1699 | 3343 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6K9A_A | 1.03e-15 | 3521 | 3781 | 18 | 269 | Thecomplex of NrS-1 N terminal domain (1-305) with dGTP [Nitratiruptor phage NrS-1],6K9B_A Apo structure of NrS-1 N terminal domain N305 [Nitratiruptor phage NrS-1],6K9B_B Apo structure of NrS-1 N terminal domain N305 [Nitratiruptor phage NrS-1] |
| 7RR4_A | 1.05e-15 | 3537 | 3781 | 27 | 268 | ChainA, Primase [Nitratiruptor phage NrS-1] |
| 6A9W_A | 1.27e-15 | 3521 | 3781 | 37 | 288 | Structureof the bifunctional DNA primase-polymerase from phage NrS-1 [Nitratiruptor phage NrS-1],6JON_A Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity [Nitratiruptor phage NrS-1],6JOP_A Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity [Nitratiruptor phage NrS-1],6JOQ_A Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity [Nitratiruptor phage NrS-1] |
| 7RR3_A | 5.12e-14 | 3521 | 3781 | 17 | 268 | ChainA, Primase [Nitratiruptor phage NrS-1] |
| 5AKB_A | 4.40e-10 | 263 | 350 | 11 | 99 | MutSin complex with the N-terminal domain of MutL - crystal form 1 [Escherichia coli K-12],5AKB_B MutS in complex with the N-terminal domain of MutL - crystal form 1 [Escherichia coli K-12],5AKB_E MutS in complex with the N-terminal domain of MutL - crystal form 1 [Escherichia coli K-12],5AKC_A MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_B MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_E MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_F MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_I MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKC_J MutS in complex with the N-terminal domain of MutL - crystal form 2 [Escherichia coli K-12],5AKD_A MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_B MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_E MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_F MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_I MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12],5AKD_J MutS in complex with the N-terminal domain of MutL - crystal form 3 [Escherichia coli K-12] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q71TF8 | 7.50e-39 | 916 | 2259 | 45 | 1567 | Defense against restriction protein B OS=Escherichia phage P1 OX=2886926 GN=darB PE=3 SV=1 |
| A4J5Q6 | 1.24e-18 | 262 | 351 | 3 | 93 | DNA mismatch repair protein MutS OS=Desulfotomaculum reducens (strain MI-1) OX=349161 GN=mutS PE=3 SV=1 |
| B5YJY3 | 6.32e-16 | 258 | 351 | 4 | 98 | DNA mismatch repair protein MutS OS=Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) OX=289376 GN=mutS PE=3 SV=1 |
| C0ZEZ4 | 9.63e-15 | 263 | 351 | 5 | 94 | DNA mismatch repair protein MutS OS=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) OX=358681 GN=mutS PE=3 SV=1 |
| A5D2K2 | 1.26e-14 | 265 | 350 | 1 | 86 | DNA mismatch repair protein MutS OS=Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) OX=370438 GN=mutS PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000045 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |