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CAZyme Information: MGYG000003252_02247
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides sp900761785 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides sp900761785 | |||||||||||
| CAZyme ID | MGYG000003252_02247 | |||||||||||
| CAZy Family | GH33 | |||||||||||
| CAZyme Description | Sialidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 18364; End: 19527 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH33 | 39 | 356 | 4.1e-77 | 0.9415204678362573 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd15482 | Sialidase_non-viral | 4.61e-90 | 38 | 356 | 2 | 329 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
| pfam13088 | BNR_2 | 6.73e-26 | 61 | 329 | 1 | 259 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
| pfam13859 | BNR_3 | 2.64e-10 | 52 | 219 | 1 | 165 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
| COG4409 | NanH | 2.54e-07 | 30 | 374 | 253 | 669 | Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
| smart00602 | VPS10 | 7.60e-04 | 75 | 322 | 188 | 429 | VPS10 domain. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUR43338.1 | 8.40e-280 | 1 | 387 | 1 | 387 |
| QIU95628.1 | 2.46e-240 | 3 | 387 | 3 | 387 |
| SEH77633.1 | 6.21e-101 | 38 | 380 | 69 | 402 |
| QUR43337.1 | 2.00e-75 | 35 | 382 | 59 | 422 |
| QIU95629.1 | 2.95e-74 | 35 | 382 | 57 | 420 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7MHU_A | 1.73e-78 | 35 | 382 | 35 | 398 | ChainA, Exo-alpha-sialidase [Bacteroides acidifaciens],7MHU_B Chain B, Exo-alpha-sialidase [Bacteroides acidifaciens] |
| 6MNJ_A | 1.26e-32 | 37 | 352 | 187 | 523 | Hadzamicrobial sialidase Hz136 [Alistipes],6MNJ_B Hadza microbial sialidase Hz136 [Alistipes] |
| 1EUR_A | 4.72e-28 | 43 | 350 | 18 | 344 | Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens] |
| 7LBU_A | 2.74e-27 | 50 | 350 | 94 | 413 | ChainA, Exo-alpha-sialidase [Cutibacterium acnes],7LBV_A Chain A, Exo-alpha-sialidase [Cutibacterium acnes] |
| 1EUT_A | 3.75e-27 | 43 | 350 | 18 | 344 | Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P31206 | 4.64e-27 | 42 | 352 | 195 | 528 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
| Q02834 | 2.30e-26 | 43 | 350 | 60 | 386 | Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1 |
| P15698 | 8.49e-24 | 29 | 369 | 31 | 404 | Sialidase OS=Paeniclostridium sordellii OX=1505 PE=1 SV=1 |
| P29767 | 2.15e-23 | 39 | 387 | 384 | 839 | Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1 |
| Q8WWR8 | 2.90e-21 | 32 | 284 | 4 | 282 | Sialidase-4 OS=Homo sapiens OX=9606 GN=NEU4 PE=1 SV=3 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.001002 | 0.375330 | 0.622883 | 0.000370 | 0.000222 | 0.000191 |