You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000003259_00586
You are here: Home > Sequence: MGYG000003259_00586
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | HGM14224 sp900761905 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_G; SHA-98; DTUO25; HGM14224; HGM14224; HGM14224 sp900761905 | |||||||||||
| CAZyme ID | MGYG000003259_00586 | |||||||||||
| CAZy Family | GT5 | |||||||||||
| CAZyme Description | Glycogen synthase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 21467; End: 22906 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT5 | 6 | 463 | 2.2e-93 | 0.9872881355932204 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03791 | GT5_Glycogen_synthase_DULL1-like | 8.72e-90 | 6 | 462 | 5 | 472 | Glycogen synthase GlgA and similar proteins. This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms. |
| COG0297 | GlgA | 1.56e-80 | 1 | 464 | 1 | 477 | Glycogen synthase [Carbohydrate transport and metabolism]. |
| PRK00654 | glgA | 5.90e-64 | 15 | 462 | 16 | 460 | glycogen synthase GlgA. |
| cd03801 | GT4_PimA-like | 2.57e-52 | 76 | 462 | 28 | 365 | phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. |
| cd03800 | GT4_sucrose_synthase | 3.76e-43 | 93 | 459 | 71 | 397 | sucrose-phosphate synthase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADT84626.1 | 2.40e-136 | 1 | 472 | 1 | 454 |
| ALM75822.1 | 3.40e-136 | 1 | 472 | 1 | 454 |
| AHF81032.1 | 5.49e-135 | 1 | 472 | 1 | 454 |
| AIF69408.1 | 8.03e-135 | 1 | 466 | 1 | 448 |
| EHR79588.1 | 3.92e-132 | 1 | 472 | 1 | 453 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3FRO_A | 4.77e-102 | 1 | 466 | 3 | 431 | Crystalstructure of Pyrococcus abyssi glycogen synthase with open and closed conformations [Pyrococcus abyssi],3FRO_B Crystal structure of Pyrococcus abyssi glycogen synthase with open and closed conformations [Pyrococcus abyssi],3FRO_C Crystal structure of Pyrococcus abyssi glycogen synthase with open and closed conformations [Pyrococcus abyssi] |
| 2BIS_A | 4.92e-102 | 1 | 466 | 4 | 432 | Structureof glycogen synthase from Pyrococcus abyssi [Pyrococcus abyssi],2BIS_B Structure of glycogen synthase from Pyrococcus abyssi [Pyrococcus abyssi],2BIS_C Structure of glycogen synthase from Pyrococcus abyssi [Pyrococcus abyssi] |
| 3L01_A | 1.08e-100 | 1 | 463 | 3 | 428 | ChainA, GlgA glycogen synthase [Pyrococcus abyssi],3L01_B Chain B, GlgA glycogen synthase [Pyrococcus abyssi] |
| 2BFW_A | 3.05e-47 | 234 | 440 | 4 | 191 | Structureof the C domain of glycogen synthase from Pyrococcus abyssi [Pyrococcus abyssi] |
| 6LFL_A | 2.01e-44 | 170 | 440 | 151 | 392 | Crystalstructure of a class A GPCR [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9CHM9 | 8.24e-39 | 14 | 462 | 15 | 475 | Glycogen synthase OS=Lactococcus lactis subsp. lactis (strain IL1403) OX=272623 GN=glgA PE=3 SV=2 |
| B0S264 | 1.01e-37 | 14 | 462 | 15 | 469 | Glycogen synthase OS=Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) OX=334413 GN=glgA PE=3 SV=1 |
| Q8UK38 | 7.44e-36 | 1 | 462 | 1 | 469 | Glycogen synthase 2 OS=Agrobacterium fabrum (strain C58 / ATCC 33970) OX=176299 GN=glgA2 PE=3 SV=2 |
| A3PBY3 | 9.08e-35 | 1 | 474 | 1 | 463 | Glycogen synthase OS=Prochlorococcus marinus (strain MIT 9301) OX=167546 GN=glgA PE=3 SV=1 |
| B8GNA4 | 1.71e-34 | 14 | 462 | 15 | 478 | Glycogen synthase OS=Thioalkalivibrio sulfidiphilus (strain HL-EbGR7) OX=396588 GN=glgA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000057 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |