CAZyme Information: MGYG000003267_00620

Basic Information

• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; Xanthomonadaceae; Stenotrophomonas
• CAZyme ID: MGYG000003267_00620
• CAZy Family: GT51
• CAZyme Description: Biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
240	MGYG000003267_133|CGC1	26810.93	10.927

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003267	1766327	MAG	El Salvador	South America

• Gene Location: Start: 2508; End: 3230 Strand: -

Full Sequence      

MGTVLPAGKRGRRWRWVVFIPVLLAALSVLQVVVLRWVDPPFSMVMAADQAGRWLHGPQR
NLLAHDWVGREQMAGCVGISLVAAEDQQFPFHRGFDTAAIASALDHNAAGGAVRGASTIS
QQVAKNLFLWQGRSWLRKGLEAWYTVWIELLWPKARILEVYANIAQMGDGLYGVQAASRR
YFGRDAAELNSEQCARLAAVLPSPLRYNAQHPGPYVQRRVRWIQRQVRQLGGASYLEAGR

Enzyme Prediction     

No EC number prediction in MGYG000003267_00620.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	65	226	2.9e-48	0.9152542372881356

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK00056	mtgA	1.28e-114	6	237	1	233	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional
TIGR02070	mono_pep_trsgly	8.40e-81	15	232	6	223	monofunctional biosynthetic peptidoglycan transglycosylase. This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744	MrcB	4.92e-68	6	238	3	251	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
pfam00912	Transgly	3.93e-56	65	223	13	172	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG5009	MrcA	1.21e-29	80	231	82	234	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QGY75780.1	4.02e-100	2	238	10	246
AJC44541.1	2.31e-99	4	238	11	246
QEN94329.1	3.28e-99	2	238	10	246
AKK68418.1	3.28e-99	2	238	10	246
QSQ54603.1	3.28e-99	2	238	10	246

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2OQO_A	9.02e-26	80	219	35	176	Crystalstructure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis [Aquifex aeolicus VF5],3D3H_A Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A [Aquifex aeolicus],3NB7_A Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin [Aquifex aeolicus]
3NB6_A	3.49e-25	80	219	35	176	Crystalstructure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin [Aquifex aeolicus]
7U4H_A	2.86e-18	80	208	55	182	ChainA, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX],7U4H_B Chain B, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX]
4OON_A	2.31e-17	80	231	54	206	Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
5U2G_A	5.80e-17	80	208	55	184	2.6Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20],5U2G_B 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8PI51	3.25e-95	9	238	15	245	Biosynthetic peptidoglycan transglycosylase OS=Xanthomonas axonopodis pv. citri (strain 306) OX=190486 GN=mtgA PE=3 SV=1
Q4UXB0	1.32e-94	6	238	13	245	Biosynthetic peptidoglycan transglycosylase OS=Xanthomonas campestris pv. campestris (strain 8004) OX=314565 GN=mtgA PE=3 SV=1
B0RQA5	1.32e-94	6	238	13	245	Biosynthetic peptidoglycan transglycosylase OS=Xanthomonas campestris pv. campestris (strain B100) OX=509169 GN=mtgA PE=3 SV=1
Q8P6V1	1.32e-94	6	238	13	245	Biosynthetic peptidoglycan transglycosylase OS=Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=mtgA PE=3 SV=1
Q3BQP8	1.15e-93	9	237	15	244	Biosynthetic peptidoglycan transglycosylase OS=Xanthomonas campestris pv. vesicatoria (strain 85-10) OX=316273 GN=mtgA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000031	0.000005	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
16	38