CAZyme Information: MGYG000003283_00182

Basic Information

• Species: 51-20 sp900762565
• Lineage: Bacteria; Proteobacteria; Alphaproteobacteria; RF32; CAG-239; 51-20; 51-20 sp900762565
• CAZyme ID: MGYG000003283_00182
• CAZy Family: GT11
• CAZyme Description: O-antigen biosynthesis glycosyltransferase WbnK

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
282		33614.48	7.1801

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003283	1475140	MAG	United States	North America

• Gene Location: Start: 13452; End: 14300 Strand: +

Full Sequence      

MFNMVKKVFVHLSDGLGNQMFQYAFGVSLKKRCGVRVYYDNAFFLSQTFRKYALHCFGII
IKKYSKTSAEKRSELQLKMVKEKQDSIYDESLYHIENNNYYKGYFQSYKYIAPYRKDILK
IFRPVYPLDDANQEILDKIKSVNAVSLHVRRTDYLKEKELSIRGICNPDYYEHAVQYIKQ
HVENPVFFIFSDDIEWCRENIDPDAEHVFVDINDGEKGYFDMFLMQNCKHNIIANSSFSW
WGAWLNEHPEKIVIAPKIWMLSWNEPEENAGRDLIPPEWIRL

Enzyme Prediction     

No EC number prediction in MGYG000003283_00182.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT11	9	281	3.2e-78	0.9855072463768116

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd11301	Fut1_Fut2_like	2.86e-74	6	261	1	257	Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531	Glyco_transf_11	1.30e-27	8	280	2	295	Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AZB31070.1	6.71e-63	8	282	2	286
QTL97698.1	5.07e-60	10	282	4	274
AZZ36566.1	5.26e-59	8	282	2	284
AVG15871.1	6.08e-59	8	282	2	290
AOZ51591.1	2.42e-58	8	282	2	290

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q58YV9	5.24e-36	12	282	5	302	O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1
Q866C9	1.02e-12	145	282	216	353	Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Lagothrix lagotricha OX=9519 GN=FUT1 PE=3 SV=1
Q866F0	2.53e-12	145	282	216	353	Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Saimiri boliviensis boliviensis OX=39432 GN=FUT1 PE=3 SV=1
Q866E8	2.53e-12	145	282	216	353	Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Sapajus apella OX=9515 GN=FUT1 PE=3 SV=1
Q866C7	2.53e-12	145	282	216	353	Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Ateles belzebuth OX=9507 GN=FUT1 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000043	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003283_00182.