CAZyme Information: MGYG000003326_02291

Basic Information

• Species: Blautia sp900541955
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia; Blautia sp900541955
• CAZyme ID: MGYG000003326_02291
• CAZy Family: PL12
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
667	MGYG000003326_52|CGC2	77706.06	5.8868

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003326	2715873	MAG	United States	North America

• Gene Location: Start: 29137; End: 31140 Strand: +

Full Sequence      

MNKKTYFERQKNRYKEGEFRWCTQTVLQQHKENCRQIMRIADEAVRLEFLFDLPWDMERT
YKIEKFQYPIDWTYMPTDDSEFIYQMNRHRYFICLGQAYAMTGNEKYAEAFVRILRDWIE
HVPLNQESKKVTWREIEAGIRGENWTKSILYFENSSLVDDDFMELFTKSLEEHGEYLFNA
KRGFQISSNWGVLENHGLLFIGLALGKEIYTETALKRLEQEVQIQIFSDGVHWEQSCMYH
NEVLHCVLETIHMLQAWGRKIPEKITEAARRMAMVNVAWKKPDGCQPLTGDSDETNVEDM
LAVSAILLAKEGKKEAEVLKGCAGQYPDYESIWDLRREGAEIYERILGRVPQQTNFMLEE
SGNYYVRNNWERNGEYLHFRNGCLGGGHGHNDKLHIDVVSEGEDVLVDAGRYQYTYHEKN
RIWLKSAYAHNTLLVDNKDFMEYTDAWGSEYAAPELRISPIQKAGYLVLEGAHTGYLQKG
VQVLLKRMVVVLEPGVYVLADMAYTSEKHTYSRLFHFNNQGNLVCEDNRIVYNGTRAKME
LVFPQENISFHRIESKISRHYNLCEKNEAVSAEAQGEGQTAMFAVLAGKQMQPVQVSMRS
VYNPVRNCALKEEYAQGLYIRTDNHEYRLIFRYKDLTGPHDLLQMDSCMGIGRLLISADG
ENTISFA

Enzyme Prediction     

No EC number prediction in MGYG000003326_02291.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
PL12	361	501	1.7e-42	0.9925925925925926

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam16889	Hepar_II_III_N	1.84e-40	39	302	58	327	Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940	Hepar_II_III	2.42e-17	385	518	36	165	Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASM70659.1	0.0	1	667	1	667
SEU00790.1	5.69e-183	1	656	1	657
BAR73172.1	1.61e-182	1	656	1	657
ADL06674.1	2.07e-180	1	656	1	657
QRV19257.1	2.07e-180	1	656	1	657

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4MMH_A	4.73e-25	70	441	98	456	Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4MMI_A	4.73e-25	70	441	98	456	Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
5JMD_A	1.53e-24	70	446	102	480	HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A	1.10e-23	70	446	102	480	HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4FNV_A	2.06e-22	70	439	141	518	CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q59289	2.73e-24	70	441	122	480	Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
C7EXL6	2.78e-24	39	439	87	485	Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q89YR9	1.13e-21	70	439	141	518	Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000063	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003326_02291.