CAZyme Information: MGYG000003335_01706

Basic Information

• Species: GCA-900066135 sp900543575
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; GCA-900066135; GCA-900066135 sp900543575
• CAZyme ID: MGYG000003335_01706
• CAZy Family: GH76
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
370	MGYG000003335_187|CGC1	42176.51	4.3841

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003335	3295822	MAG	China	Asia

• Gene Location: Start: 1559; End: 2671 Strand: -

Full Sequence      

MRIFSTKIRKRILCAAAAAVIAVSGTGMTAMPVFGKETEGGQEADMRVEQAEKAMQNFLD
RFYVVDEDNDRGEIVGEFFWTRAEMFEVVVDAYEKTGEEKYKDLMAQMYRGFVKSYGEEW
SDNDFNDDIMWMTIGCARAYELTGETFYKEQAEHHFKLVFDRAWNDDLGGGLLWKTDQTC
KNACINGPAAIAGCLLYRITKEEDYLEKAKQIYQWQLDTLCQGNGAVSDNIESDGKINTW
CSTYNQGTFIGASQLLWELTGEQKYLDEAILAADYTMHEMFHDGVINTEAEGNDLPGFKG
ILARWLGKLVNEGGQEQYREWMELNAETAWKNQNAKGLMWTLWGEKTQDTFYMPWGCSAA
IAQLFAVIHK

Enzyme Prediction     

No EC number prediction in MGYG000003335_01706.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH76	50	346	4.6e-79	0.8687150837988827

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam03663	Glyco_hydro_76	7.31e-48	51	341	6	331	Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
COG4833	COG4833	2.33e-40	46	348	1	331	Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].
cd04434	LanC_like	6.71e-04	92	241	64	217	Cyclases involved in the biosynthesis of lantibiotics, and similar proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain thioether cross-links called lanthionines (Lans) or methyllanthionines (MeLans), in addition to 2,3-didehydroalanine (Dha) and (Z)-2,3-didehydrobutyrine (Dhb). These unusual amino acids are introduced by the dehydration of serine and threonine residues, followed by thioether formation via addition of cysteine thiols, catalysed by LanB and LanC or LanM. LanC, the cyclase component, is a zinc metalloprotein, whose bound metal has been proposed to activate the thiol substrate for nucleophilic addition. A related domain is also present in LanM and other pro- and eukaryotic proteins with poorly characterized functions.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QOV19890.1	1.87e-107	45	362	25	348
AYD48939.1	2.53e-78	76	365	198	493
QEC70572.1	3.02e-75	79	365	201	493
QRK04753.1	3.20e-72	62	362	49	358
QJE95016.1	1.16e-71	51	359	38	347

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4D4A_A	1.20e-69	79	364	59	359	ChainA, Alpha-1,6-mannanase [Niallia circulans],4D4A_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4B_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4B_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4C_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4C_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4D_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4D_B Chain B, Alpha-1,6-mannanase [Niallia circulans],5N0F_A Chain A, Alpha-1,6-mannanase [Niallia circulans],5N0F_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBX_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBX_B Chain B, Alpha-1,6-mannanase [Niallia circulans],7NL5_A Chain A, Alpha-1,6-mannanase [Niallia circulans]
4BOK_A	2.60e-69	79	364	38	338	ChainA, Alpha-1,6-mannanase [Niallia circulans]
5AGD_A	6.67e-69	79	364	59	359	ChainA, Alpha-1,6-mannanase [Niallia circulans],5AGD_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBM_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_B Chain B, Alpha-1,6-mannanase [Niallia circulans]
4BOJ_A	2.23e-68	80	364	42	341	ChainA, Alpha-1,6-mannanase [Niallia circulans],4BOJ_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4BOJ_C Chain C, Alpha-1,6-mannanase [Niallia circulans]
5M77_A	2.96e-67	79	364	72	372	ChainA, Alpha-1,6-mannanase [Niallia circulans],5M77_B Chain B, Alpha-1,6-mannanase [Niallia circulans]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q9P6I3	2.59e-07	78	307	55	311	Putative mannan endo-1,6-alpha-mannosidase C1198.07c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC1198.07c PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000917	0.997822	0.000501	0.000343	0.000196	0.000174

TMHMM  Annotations     

start	end
12	34