CAZyme Information: MGYG000003404_00642

Basic Information

• Species: Lactococcus hircilactis
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Lactococcus; Lactococcus hircilactis
• CAZyme ID: MGYG000003404_00642
• CAZy Family: GT51
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
304		32579.31	5.2792

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003404	1333590	MAG	United States	North America

• Gene Location: Start: 2957; End: 3871 Strand: -

Full Sequence      

MMSFTEALDVSYNIPAFWTYKAVYKDGQGAKPYMSKMGYNIKDYSIESLPLGGGVDPTVV
QHTNGYATLANGGKYVPYYLISSITDDKGNVIYEHSNPDPVQVYSEATATIMENMLQGVI
KAQKTSKFYSDLQGLNPNLANQVAWAGKTGTTDYYTDVWLMLSTPTVTLGGWAGHDDNSP
MTSNVGYFNNAAYMANLVNAINTADPNIFGSGKTFKDPNTDPNVTKSTVLESTGEKPATV
NGKAVSGKTVTSFWTTKSGAPNTTYKFAIGGSDADYVDAWNKILPGMPASSGTTPSASSA
QPKQ

Enzyme Prediction     

No EC number prediction in MGYG000003404_00642.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	1.81e-47	1	262	411	661	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	2.97e-29	2	182	342	508	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009	MrcA	7.07e-18	33	181	538	697	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
COG4953	PbpC	7.57e-10	1	240	381	596	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
COG0768	FtsI	2.36e-09	58	158	443	535	Cell division protein FtsI/penicillin-binding protein 2 [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QSE63122.1	7.39e-141	1	285	506	799
AGV72368.1	7.39e-141	1	285	506	799
CAL97007.1	2.94e-140	1	285	506	799
ADJ59420.1	2.94e-140	1	285	506	799
QTA75826.1	2.94e-140	1	285	506	799

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2BG1_A	2.55e-100	1	288	209	494	Activesite restructuring regulates ligand recognition in classA Penicillin-binding proteins (PBPs) [Streptococcus pneumoniae R6],2XD5_A Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b [Streptococcus pneumoniae R6],2XD5_B Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b [Streptococcus pneumoniae R6]
2UWX_A	2.55e-100	1	288	209	494	Activesite restructuring regulates ligand recognition in class A penicillin-binding proteins [Streptococcus pneumoniae R6]
2XD1_A	2.55e-100	1	288	209	494	ACTIVESITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS [Streptococcus pneumoniae R6],2XD1_B ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS [Streptococcus pneumoniae R6]
2Y2G_A	5.10e-100	1	288	209	494	Penicillin-BindingProtein 1b (Pbp-1b) In Complex With An Alkyl Boronate (A01) [Streptococcus pneumoniae R6],2Y2G_B Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (A01) [Streptococcus pneumoniae R6],2Y2H_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Za2) [Streptococcus pneumoniae R6],2Y2H_B Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Za2) [Streptococcus pneumoniae R6],2Y2I_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Za3) [Streptococcus pneumoniae R6],2Y2J_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Za4) [Streptococcus pneumoniae R6],2Y2K_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Za5) [Streptococcus pneumoniae R6],2Y2L_A Penicillin-binding Protein 1b (pbp-1b) In Complex With An Alkyl Boronate (e06) [Streptococcus pneumoniae R6],2Y2L_B Penicillin-binding Protein 1b (pbp-1b) In Complex With An Alkyl Boronate (e06) [Streptococcus pneumoniae R6],2Y2M_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (E08) [Streptococcus pneumoniae R6],2Y2N_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (E07) [Streptococcus pneumoniae R6],2Y2O_A Penicillin-binding Protein 1b (pbp-1b) In Complex With An Alkyl Boronate (eo9) [Streptococcus pneumoniae R6],2Y2P_A Penicillin-binding protein 1b (pbp-1b) in complex with an alkyl boronate (z10) [Streptococcus pneumoniae R6],2Y2Q_A Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Z06) [Streptococcus pneumoniae R6],2Y2Q_B Penicillin-Binding Protein 1b (Pbp-1b) In Complex With An Alkyl Boronate (Z06) [Streptococcus pneumoniae R6]
2JCH_A	7.83e-100	1	284	178	459	Structuraland mechanistic basis of penicillin binding protein inhibition by lactivicins [Streptococcus pneumoniae R6]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P38050	9.66e-13	2	176	405	571	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2
P40750	1.72e-11	58	176	491	598	Penicillin-binding protein 4 OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpD PE=1 SV=2
Q68VU2	3.57e-09	34	176	537	690	Penicillin-binding protein 1A OS=Rickettsia typhi (strain ATCC VR-144 / Wilmington) OX=257363 GN=mrcA PE=3 SV=1
Q4UK08	4.78e-09	34	176	537	690	Penicillin-binding protein 1A OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=mrcA PE=3 SV=1
Q9ZCE9	6.38e-09	34	176	537	690	Penicillin-binding protein 1A OS=Rickettsia prowazekii (strain Madrid E) OX=272947 GN=mrcA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000045	0.000002	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003404_00642.