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CAZyme Information: MGYG000003415_00028
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Alistipes sp900766655 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes sp900766655 | |||||||||||
| CAZyme ID | MGYG000003415_00028 | |||||||||||
| CAZy Family | GH33 | |||||||||||
| CAZyme Description | Sialidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 8961; End: 10064 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH33 | 22 | 360 | 6.2e-91 | 0.9649122807017544 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd15482 | Sialidase_non-viral | 1.36e-95 | 20 | 362 | 1 | 339 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
| pfam13088 | BNR_2 | 1.51e-26 | 45 | 343 | 2 | 280 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
| cd00260 | Sialidase | 1.42e-07 | 27 | 184 | 9 | 156 | sialidases/neuraminidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed beta-propeller fold. This hierarchy includes eubacterial, eukaryotic, and viral sialidases. |
| COG4409 | NanH | 7.35e-07 | 12 | 346 | 254 | 700 | Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BBD46002.1 | 4.15e-114 | 14 | 367 | 31 | 376 |
| AYQ36531.1 | 8.93e-109 | 1 | 358 | 11 | 362 |
| QQL50302.1 | 3.03e-104 | 22 | 362 | 36 | 373 |
| QGQ21444.1 | 2.09e-103 | 14 | 366 | 34 | 381 |
| QDT26944.1 | 2.09e-103 | 19 | 366 | 38 | 381 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7P1B_C | 1.69e-35 | 29 | 312 | 58 | 336 | ChainC, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1D_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1E_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1F_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1F_B Chain B, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1O_A Chain A, Sialidase domain-containing protein [Aspergillus terreus NIH2624],7P1O_X Chain X, Sialidase domain-containing protein [Aspergillus terreus NIH2624] |
| 6MNJ_A | 3.57e-34 | 32 | 346 | 199 | 521 | Hadzamicrobial sialidase Hz136 [Alistipes],6MNJ_B Hadza microbial sialidase Hz136 [Alistipes] |
| 6MYV_A | 1.40e-33 | 22 | 346 | 170 | 504 | Sialidase26co-crystallized with DANA-Gc [bacterium],6MYV_B Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_C Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_D Sialidase26 co-crystallized with DANA-Gc [bacterium] |
| 2BF6_A | 1.50e-33 | 22 | 346 | 12 | 429 | AtomicResolution Structure of the bacterial sialidase NanI from Clostridium perfringens in complex with alpha-Sialic Acid (Neu5Ac). [Clostridium perfringens] |
| 2VK5_A | 1.56e-33 | 22 | 346 | 12 | 429 | TheStructure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK6_A The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK7_A The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens],2VK7_B The Structure Of Clostridium Perfringens Nani Sialidase And Its Catalytic Intermediates [Clostridium perfringens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q4WQS0 | 2.83e-30 | 29 | 346 | 54 | 374 | Exo-alpha-sialidase OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=AFUA_4G13800 PE=1 SV=2 |
| P31206 | 3.12e-29 | 22 | 346 | 192 | 526 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
| Q02834 | 6.88e-29 | 25 | 348 | 59 | 388 | Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1 |
| Q9JMH7 | 2.16e-28 | 17 | 366 | 8 | 406 | Sialidase-3 OS=Mus musculus OX=10090 GN=Neu3 PE=1 SV=1 |
| A6BMK7 | 5.01e-27 | 6 | 361 | 42 | 409 | Sialidase-1 OS=Bos taurus OX=9913 GN=NEU1 PE=2 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.905547 | 0.093544 | 0.000591 | 0.000118 | 0.000067 | 0.000134 |