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CAZyme Information: MGYG000003443_00658

You are here: Home > Sequence: MGYG000003443_00658

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA1067 sp900767325
Lineage Bacteria; Verrucomicrobiota; Kiritimatiellae; RFP12; UBA1067; UBA1067; UBA1067 sp900767325
CAZyme ID MGYG000003443_00658
CAZy Family GH123
CAZyme Description Futalosine hydrolase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
691 77426.89 6.7042
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003443 1101788 MAG Fiji Oceania
Gene Location Start: 6465;  End: 8540  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003443_00658.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH123 245 643 2.3e-130 0.7286245353159851

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd09008 MTAN 2.51e-32 10 178 45 222
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.
COG0775 Pfs 1.76e-28 1 182 40 233
Nucleoside phosphorylase [Nucleotide transport and metabolism].
pfam13320 DUF4091 2.08e-21 576 636 1 66
Domain of unknown function (DUF4091). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length. There is a single completely conserved residue G that may be functionally important.
pfam01048 PNP_UDP_1 1.57e-20 11 179 49 231
Phosphorylase superfamily. Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase)
cd17877 NP_MTAN-like 1.66e-17 11 150 46 182
nucleoside phosphorylases similar to 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs), as well as futalosine nucleosidase and adenosylhopane nucleosidase. Bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QYM78770.1 1.41e-128 204 681 214 713
AYR31393.1 1.17e-103 191 636 30 486
QWO89199.1 6.22e-103 191 636 102 558
AFL77927.1 9.72e-103 266 636 174 540
QAA41011.1 4.96e-102 191 636 30 486

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5L7V_A 2.20e-90 260 637 146 518
ChainA, glycoside hydrolase [Phocaeicola vulgatus ATCC 8482],5L7V_B Chain B, glycoside hydrolase [Phocaeicola vulgatus ATCC 8482]
5L7R_A 3.26e-90 260 637 161 533
ChainA, glycoside hydrolase [Phocaeicola vulgatus ATCC 8482],5L7R_B Chain B, glycoside hydrolase [Phocaeicola vulgatus ATCC 8482],5L7U_A Chain A, Glycoside hydrolase [Phocaeicola vulgatus ATCC 8482],5L7U_B Chain B, Glycoside hydrolase [Phocaeicola vulgatus ATCC 8482]
5FQE_A 3.71e-46 258 637 140 544
Thedetails of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens],5FQE_B The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens],5FQF_A The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens],5FQF_B The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens],5FR0_A The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens]
5FQG_A 4.39e-45 258 637 140 544
Thedetails of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens],5FQH_A The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens [Clostridium perfringens]
5DK6_A 7.29e-10 3 155 62 231
CrystalStructure Of A 5'-methylthioadenosine/s-adenosylhomocysteine (mta/sah) Nucleosidase (mtan) From Colwellia Psychrerythraea 34h (cps_4743, Target Psi-029300) In Complex With Adenine At 2.27 A Resolution [Colwellia psychrerythraea 34H]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A6W3C9 6.90e-14 3 179 41 228
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Marinomonas sp. (strain MWYL1) OX=400668 GN=mtnN PE=3 SV=1
Q47UY5 1.15e-10 3 155 40 209
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) OX=167879 GN=mtnN PE=1 SV=1
C4LAP0 1.14e-08 1 155 38 204
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Tolumonas auensis (strain DSM 9187 / TA4) OX=595494 GN=mtnN PE=3 SV=1
P9WJM2 1.16e-08 8 175 47 252
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=mtnN PE=3 SV=1
P67657 1.16e-08 8 175 47 252
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=mtnN PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000029 0.000013 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003443_00658.