CAZyme Information: MGYG000003469_00233

Basic Information

• Species: Alistipes sp900768015
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes sp900768015
• CAZyme ID: MGYG000003469_00233
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
375		42816.49	8.7913

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003469	1886287	MAG	Fiji	Oceania

• Gene Location: Start: 56668; End: 57795 Strand: -

Full Sequence      

MKYYVIAGEPSGDLHGSKLMRGIRHNDPEASFRFSGGDRMAEVGGAENMLYHYKQMSFFG
FVQVAMNLRTIFRQIDDVKADIEGFNPDVIILIDYPAFNLRIAKWAKAKGIRVYYYIAPK
VWAWKERRVKQLRRYVDRLYTIFPFETEYFRGHGIEPTFCGNPLVDDIAERRSTLPTREA
YLAECGLDNRPIVALLAGSRVSEIKANLPDMVALSRKFPDYQFVVTAVPWIDKSLYDSII
ANSDVRYVCDRTQQTLAMSEAAIVTSGTATLETALMGIPEVVLYHVPWLYEKLKPYFLRI
PYISLVNINLNREAVKELVRAKLPIETSAKELAAILPGGSDRERMLRDFEELRTMIGEAG
ASERFAKDIVNSLKR

Enzyme Prediction     

No EC number prediction in MGYG000003469_00233.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	4	357	6.9e-106	0.9915254237288136

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK00025	lpxB	3.47e-106	1	375	2	377	lipid-A-disaccharide synthase; Reviewed
COG0763	LpxB	6.35e-99	1	375	2	381	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
pfam02684	LpxB	2.37e-69	4	352	2	358	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
TIGR00215	lpxB	8.46e-66	5	370	10	383	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK14089	PRK14089	9.61e-53	1	372	2	347	lipid-A-disaccharide synthase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AFL77950.1	1.13e-163	1	373	1	373
BBL06737.1	1.52e-161	1	374	1	374
BBL11605.1	1.01e-159	1	374	1	374
BBL08813.1	1.01e-159	1	374	1	374
BBL00808.1	5.80e-159	1	374	1	374

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8S_A	2.38e-35	5	370	11	378	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]
5W8N_A	4.58e-35	5	370	11	378	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q1D393	2.35e-66	5	373	9	378	Lipid-A-disaccharide synthase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxB PE=3 SV=1
Q74AT9	1.06e-60	5	373	11	380	Lipid-A-disaccharide synthase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) OX=243231 GN=lpxB PE=3 SV=1
Q2LVL8	8.00e-60	5	375	8	380	Lipid-A-disaccharide synthase OS=Syntrophus aciditrophicus (strain SB) OX=56780 GN=lpxB PE=3 SV=1
Q39T49	8.92e-59	5	373	11	380	Lipid-A-disaccharide synthase OS=Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15) OX=269799 GN=lpxB PE=3 SV=1
B8JE78	1.72e-58	5	374	13	383	Lipid-A-disaccharide synthase OS=Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258) OX=455488 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000038	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003469_00233.