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CAZyme Information: MGYG000003514_02137
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Fibrobacter_A intestinalis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae; Fibrobacter_A; Fibrobacter_A intestinalis | |||||||||||
| CAZyme ID | MGYG000003514_02137 | |||||||||||
| CAZy Family | GH10 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 365; End: 2221 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH10 | 31 | 346 | 7e-62 | 0.933993399339934 |
| CBM6 | 402 | 528 | 4.9e-26 | 0.8985507246376812 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| smart00633 | Glyco_10 | 4.17e-60 | 55 | 347 | 1 | 263 | Glycosyl hydrolase family 10. |
| cd04080 | CBM6_cellulase-like | 3.74e-38 | 382 | 529 | 1 | 144 | Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase). This family includes carbohydrate binding module 6 (CBM6) domains that are appended to several glycoside hydrolase (GH) domains, including GH5 (cellulase) and GH16, as well as to coagulation factor 5/8 carbohydrate-binding domains. CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. The CBM6s are appended to GHs that display a diversity of substrate specificities. For some members of this family information is available about the specific substrates of the appended GH domains. It includes the CBM domains of various enzymes involved in cell wall degradation including, an extracellular beta-1,3-glucanase from Lysobacter enzymogenes encoded by the gluC gene (its catalytic domain belongs to the GH16 family), the tandem CBM domains of Pseudomonas sp. PE2 beta-1,3(4)-glucanase A (its catalytic domain also belongs to GH16), and a family 6 CBM from Cellvibrio mixtus Endoglucanase 5A (CmCBM6) which binds to the beta1,4-beta1,3-mixed linked glucans lichenan, and barley beta-glucan, cello-oligosaccharides, insoluble forms of cellulose, the beta1,3-glucan laminarin, and xylooligosaccharides, and the CBM6 of Fibrobacter succinogenes S85 XynD xylanase, appended to a GH10 domain, and Cellvibrio japonicas Cel5G appended to a GH5 (cellulase) domain. GH5 (cellulase) family includes enzymes with several known activities such as endoglucanase, beta-mannanase, and xylanase, which are involved in the degradation of cellulose and xylans. GH16 family includes enzymes with lichenase, xyloglucan endotransglycosylase (XET), and beta-agarase activities. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. For CmCBM6 it has been shown that these two binding sites have different ligand specificities. |
| COG3693 | XynA | 5.17e-35 | 17 | 352 | 26 | 342 | Endo-1,4-beta-xylanase, GH35 family [Carbohydrate transport and metabolism]. |
| pfam00331 | Glyco_hydro_10 | 5.93e-34 | 24 | 348 | 13 | 309 | Glycosyl hydrolase family 10. |
| smart00606 | CBD_IV | 1.64e-24 | 404 | 528 | 1 | 129 | Cellulose Binding Domain Type IV. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AAG02560.1 | 0.0 | 1 | 618 | 1 | 623 |
| ACX75384.1 | 0.0 | 1 | 618 | 1 | 623 |
| ADL26381.1 | 0.0 | 1 | 618 | 1 | 623 |
| AAG36764.1 | 0.0 | 1 | 618 | 1 | 623 |
| ADX05720.1 | 1.26e-212 | 7 | 618 | 9 | 595 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4PN2_A | 1.67e-40 | 18 | 352 | 1 | 301 | Crystalstructure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri complexed with xylotriose [Xanthomonas citri pv. citri str. 306],4PN2_B Crystal structure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri complexed with xylotriose [Xanthomonas citri pv. citri str. 306] |
| 4PMX_A | 1.71e-40 | 18 | 352 | 1 | 301 | Crystalstructure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri in the native form [Xanthomonas citri pv. citri str. 306] |
| 4PMY_A | 5.73e-40 | 20 | 352 | 2 | 300 | Crystalstructure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri complexed with xylose [Xanthomonas citri pv. citri str. 306],4PMY_B Crystal structure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri complexed with xylose [Xanthomonas citri pv. citri str. 306],4PMZ_A Crystal structure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri complexed with xylobiose [Xanthomonas citri pv. citri str. 306],4PMZ_B Crystal structure of GH10 endo-b-1,4-xylanase (XynB) from Xanthomonas axonopodis pv citri complexed with xylobiose [Xanthomonas citri pv. citri str. 306] |
| 1VBR_A | 5.54e-14 | 46 | 328 | 42 | 289 | Crystalstructure of complex xylanase 10B from Thermotoga maritima with xylobiose [Thermotoga maritima],1VBR_B Crystal structure of complex xylanase 10B from Thermotoga maritima with xylobiose [Thermotoga maritima],1VBU_A Crystal structure of native xylanase 10B from Thermotoga maritima [Thermotoga maritima],1VBU_B Crystal structure of native xylanase 10B from Thermotoga maritima [Thermotoga maritima] |
| 3NIY_A | 8.39e-14 | 46 | 328 | 58 | 305 | Crystalstructure of native xylanase 10B from Thermotoga petrophila RKU-1 [Thermotoga petrophila RKU-1],3NIY_B Crystal structure of native xylanase 10B from Thermotoga petrophila RKU-1 [Thermotoga petrophila RKU-1],3NJ3_A Crystal structure of xylanase 10B from Thermotoga petrophila RKU-1 in complex with xylobiose [Thermotoga petrophila RKU-1],3NJ3_B Crystal structure of xylanase 10B from Thermotoga petrophila RKU-1 in complex with xylobiose [Thermotoga petrophila RKU-1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P23030 | 2.58e-55 | 27 | 347 | 323 | 592 | Endo-1,4-beta-xylanase B OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=xynB PE=1 SV=2 |
| W0HFK8 | 1.35e-12 | 25 | 331 | 43 | 308 | Endo-1,4-beta-xylanase 1 OS=Rhizopus oryzae OX=64495 GN=xyn1 PE=1 SV=1 |
| Q6PRW6 | 1.63e-12 | 25 | 331 | 43 | 308 | Endo-1,4-beta-xylanase OS=Penicillium chrysogenum OX=5076 GN=Xyn PE=1 SV=1 |
| P29417 | 1.63e-12 | 25 | 331 | 43 | 308 | Endo-1,4-beta-xylanase OS=Penicillium chrysogenum OX=5076 GN=XYLP PE=1 SV=2 |
| P23556 | 2.66e-12 | 46 | 331 | 48 | 313 | Endo-1,4-beta-xylanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=xynA PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000226 | 0.999166 | 0.000153 | 0.000155 | 0.000144 | 0.000135 |