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CAZyme Information: MGYG000003526_00251

You are here: Home > Sequence: MGYG000003526_00251

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-138; UBA1685;
CAZyme ID MGYG000003526_00251
CAZy Family GH23
CAZyme Description Membrane-bound lytic murein transglycosylase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
221 24584.41 9.8093
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003526 1880479 MAG Fiji Oceania
Gene Location Start: 2785;  End: 3450  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003526_00251.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH23 83 208 9.7e-32 0.7851851851851852

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd16896 LT_Slt70-like 4.40e-78 67 207 2 143
uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd13401 Slt70-like 3.80e-55 65 204 2 142
70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.
cd00254 LT-like 1.23e-42 84 207 1 109
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
COG0741 MltE 1.53e-32 65 221 135 293
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].
pfam01464 SLT 2.65e-31 73 178 1 103
Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AYH39946.1 6.90e-50 46 216 26 195
AWZ48130.1 4.49e-49 37 216 4 184
QWT54455.1 3.29e-48 38 215 28 206
VTQ87399.1 1.06e-47 37 215 4 183
AEY66639.1 1.19e-47 36 218 12 194

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6FBT_A 3.54e-23 65 204 445 585
ChainA, Lytic murein transglycosylase [Pseudomonas aeruginosa]
5OHU_A 3.64e-23 65 204 474 614
TheX-ray Structure of Lytic Transglycosylase Slt from Pseudomonas aeruginosa [Pseudomonas aeruginosa]
6FCQ_A 8.94e-23 65 204 445 585
ChainA, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCR_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCS_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCU_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa]
6FC4_A 8.95e-23 65 204 446 586
ChainA, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa]
5MPQ_A 1.00e-21 57 215 400 559
BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O64046 1.78e-20 64 210 1417 1543
Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1
O31976 1.78e-20 64 210 1417 1543
SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2
O31608 1.93e-20 73 206 64 177
Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1
P0AGC3 6.74e-20 60 212 472 626
Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1
P0AGC4 6.74e-20 60 212 472 626
Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999951 0.000063 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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