CAZyme Information: MGYG000003548_01847

Basic Information

• Species: QALS01 sp900769545
• Lineage: Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; Borkfalkiaceae; QALS01; QALS01 sp900769545
• CAZyme ID: MGYG000003548_01847
• CAZy Family: GH29
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
315		36301.18	4.7554

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003548	2291640	MAG	Fiji	Oceania

• Gene Location: Start: 1316; End: 2263 Strand: +

Full Sequence      

MANKEWFKEAKFGMMVHFGLYSLLAGEWKGKRMDMIAEWAQSCFQIPIKEYEKLMEAFNP
IYFNADEWCDLAVAAGMKYIVVTTKHHEGFALFDSKVDDYNVMHTPFGRDIIKEISLACR
KRGLKFGIYYSQELDWHEEHGGGYTETFETNQGKPWTNFWDFPNTVKNFEICFRKKIIPQ
VTELLTNYGDIDLIWFDTPQDITKEQSVELYNLVKKYQPDCMINSRIGNGMGDYGSSGDN
ETDADSNGMLFEVPATLNDTWGYKAYDQNWKDADTVLKIKEDLNSRGINYLLNVGPDPLG
RIPAPSIDILKALNK

Enzyme Prediction     

No EC number prediction in MGYG000003548_01847.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH29	3	314	2.3e-90	0.846820809248555

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam01120	Alpha_L_fucos	1.71e-82	5	313	20	324	Alpha-L-fucosidase.
smart00812	Alpha_L_fucos	1.27e-80	5	315	21	328	Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis.
COG3669	AfuC	4.53e-36	17	313	1	308	Alpha-L-fucosidase [Carbohydrate transport and metabolism].
pfam14871	GHL6	2.94e-07	64	197	1	134	Hypothetical glycosyl hydrolase 6. GHL6 is a family of hypothetical glycoside hydrolases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUO31265.1	2.99e-133	5	315	6	353
ALB28421.1	3.53e-130	3	314	4	335
AYE37750.1	5.82e-127	3	315	4	336
AIS08437.1	1.92e-125	3	315	6	337
ARY92767.1	5.04e-124	5	312	6	334

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6O18_A	4.05e-122	3	312	4	334	ChainA, AlfC [Lacticaseibacillus casei],6O18_B Chain B, AlfC [Lacticaseibacillus casei],6O18_C Chain C, AlfC [Lacticaseibacillus casei],6O18_D Chain D, AlfC [Lacticaseibacillus casei],6O1A_A Chain A, AlfC [Lacticaseibacillus casei],6O1A_B Chain B, AlfC [Lacticaseibacillus casei],6O1A_C Chain C, AlfC [Lacticaseibacillus casei],6O1A_D Chain D, AlfC [Lacticaseibacillus casei]
6O1J_A	1.64e-121	3	312	4	334	ChainA, AlfC [Lacticaseibacillus casei],6O1J_B Chain B, AlfC [Lacticaseibacillus casei],6O1J_C Chain C, AlfC [Lacticaseibacillus casei],6O1J_D Chain D, AlfC [Lacticaseibacillus casei],6O1J_E Chain E, AlfC [Lacticaseibacillus casei],6O1J_F Chain F, AlfC [Lacticaseibacillus casei],6O1J_G Chain G, AlfC [Lacticaseibacillus casei],6O1J_H Chain H, AlfC [Lacticaseibacillus casei]
6O1I_A	3.29e-121	3	312	4	334	ChainA, AlfC [Lacticaseibacillus casei],6O1I_B Chain B, AlfC [Lacticaseibacillus casei],6O1I_C Chain C, AlfC [Lacticaseibacillus casei],6O1I_D Chain D, AlfC [Lacticaseibacillus casei]
6O1C_A	6.62e-121	3	312	4	334	ChainA, AlfC [Lacticaseibacillus casei],6O1C_B Chain B, AlfC [Lacticaseibacillus casei],6O1C_C Chain C, AlfC [Lacticaseibacillus casei],6O1C_D Chain D, AlfC [Lacticaseibacillus casei],6O1C_E Chain E, AlfC [Lacticaseibacillus casei],6O1C_F Chain F, AlfC [Lacticaseibacillus casei],6O1C_G Chain G, AlfC [Lacticaseibacillus casei],6O1C_H Chain H, AlfC [Lacticaseibacillus casei],6OHE_A Chain A, AlfC [Lacticaseibacillus casei],6OHE_B Chain B, AlfC [Lacticaseibacillus casei],6OHE_C Chain C, AlfC [Lacticaseibacillus casei],6OHE_D Chain D, AlfC [Lacticaseibacillus casei]
6GN6_A	1.26e-63	5	310	32	337	Alpha-L-fucosidaseisoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_B Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_C Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_D Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_E Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus],6GN6_F Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus [Paenibacillus thiaminolyticus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q2KIM0	2.56e-25	6	315	55	363	Tissue alpha-L-fucosidase OS=Bos taurus OX=9913 GN=FUCA1 PE=2 SV=1
Q99LJ1	3.08e-25	5	315	37	346	Tissue alpha-L-fucosidase OS=Mus musculus OX=10090 GN=Fuca1 PE=1 SV=1
Q60HF8	1.23e-24	5	315	53	362	Tissue alpha-L-fucosidase OS=Macaca fascicularis OX=9541 GN=FUCA1 PE=2 SV=1
P49713	1.35e-24	5	315	32	340	Putative alpha-L-fucosidase OS=Caenorhabditis elegans OX=6239 GN=W03G11.3 PE=3 SV=2
P17164	4.11e-24	5	315	47	356	Tissue alpha-L-fucosidase OS=Rattus norvegicus OX=10116 GN=Fuca1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000042	0.000011	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003548_01847.