CAZyme Information: MGYG000003597_00775

Basic Information

• Species: Oribacterium sp900770445
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Oribacterium; Oribacterium sp900770445
• CAZyme ID: MGYG000003597_00775
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase large subunit

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
634	MGYG000003597_45|CGC1	73047.39	5.0096

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003597	2313285	MAG	Fiji	Oceania

• Gene Location: Start: 24211; End: 26115 Strand: -

Full Sequence      

MNADIKWLDNPEIFRVNQLDAHSDHSYYVDYADMKKKDNPLSQSLNGQWAFAFSKNAASR
PCDFYKEGFDDSGFDKIMVPGHIELAGYDKIRYINTMYPWEGKEYHRGAYSLESRGAEAG
MFSEANYNPVGSYLKHFDLKPTMIGKRIRICFEGVEEAMYLWLNGQFVGYAEDSFTPSEF
DLTPYIREKDNVLAVQVHKMSTTAFLEDQDFFRFFGIFRNVTLKAVPDVHMEDVWFQPEL
NDDNKRGSVTVRMKVSATMQVAVNALFVLRDREGNVVVENSTKLQGSNGNLTGEIYTETG
VMKSWDNHHPYLYHATVELKNAENGNLLEIIPYDIGFRRVEIIDKVIYLNGKRLVITGVN
RHEWSPKTGRCIGLEEMHSDIACMLKNNINAVRTCHYPDQIPWYYLCDEAGIYVMAECNL
ESHGTFQKLGAVEPSCNVPGSIPQWKEAVMDRARTSFETFKNHTSILFWSLGNESYAGDD
IEAMNVYFKNKKDGRLVHYESAYYNRAYEDTISDIESRMYPKPQDVAAYLSDKPKKPYIL
CEFMHDMGNSMGGLGDYMKLIDEFDLYQGGFIWDFIDQAILVKDPVTGKEVLRYGGDFED
RPADYEFSANGILFADRKEKPAMQEVRYYYGLYR

Enzyme Prediction     

EC	3.2.1.23

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	23	630	7.5e-139	0.6329787234042553

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK09525	lacZ	3.05e-146	10	628	19	623	beta-galactosidase.
PRK10340	ebgA	1.34e-142	9	627	5	596	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02836	Glyco_hydro_2_C	1.76e-126	340	632	1	299	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
COG3250	LacZ	1.06e-125	43	631	13	554	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	7.58e-31	133	474	69	417	beta-D-glucuronidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBK94938.1	0.0	1	634	1	633
CBK90745.1	0.0	1	634	1	633
ACR75775.1	0.0	1	634	1	633
VCV22603.1	0.0	1	634	1	633
CBL13227.1	0.0	1	634	1	633

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6S6Z_A	5.80e-125	9	630	5	593	Structureof beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_B Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_C Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_D Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_E Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_F Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_G Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_H Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8]
6SD0_A	5.91e-125	9	630	6	594	Structureof beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_B Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_C Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_D Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8]
3DEC_A	8.75e-107	16	630	15	613	ChainA, Beta-galactosidase [Bacteroides thetaiotaomicron VPI-5482]
1F4A_A	1.33e-104	9	628	15	620	E.COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4A_B E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4A_C E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4A_D E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4H_A E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli],1F4H_B E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli],1F4H_C E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli],1F4H_D E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli]
5A1A_A	1.35e-104	9	628	16	621	2.2A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12],5A1A_B 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12],5A1A_C 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12],5A1A_D 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O07684	1.20e-275	1	634	1	628	Beta-galactosidase large subunit OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=lacL PE=3 SV=2
Q48846	2.16e-275	1	631	1	622	Beta-galactosidase large subunit OS=Latilactobacillus sakei OX=1599 GN=lacL PE=3 SV=1
Q7WTB4	5.27e-272	1	634	1	628	Beta-galactosidase large subunit OS=Lactobacillus helveticus OX=1587 GN=lacL PE=2 SV=1
Q02603	6.96e-272	1	634	1	626	Beta-galactosidase large subunit OS=Leuconostoc lactis OX=1246 GN=lacL PE=1 SV=1
P24131	7.09e-216	5	630	8	612	Beta-galactosidase OS=Clostridium acetobutylicum OX=1488 GN=cbgA PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000049	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003597_00775.