CAZyme Information: MGYG000003600_00673

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae
• CAZyme ID: MGYG000003600_00673
• CAZy Family: GT39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
621		71029.88	6.5628

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003600	1529489	MAG	Fiji	Oceania

• Gene Location: Start: 9649; End: 11514 Strand: -

Full Sequence      

MNLSLSLIFPVLLIAGLLCFFCYYIHAMIPRKGTLEWIARAETCVGPRKFSFTAPLHPME
KKDALPLILLTVLYAVTAFWNLGNTTNPQSFLNMKDEDTVSFSTSQTVSLSRVTYYSGLW
TGSYYLDYSSDGVNWESVELPQKYSRLFYWQNAELPEGQPLQAKYFQLTAASDREQMELG
ELALFDENGVQVSVQADADVAPLFDEQNIVPDAPHWMNSAYFDEIYHARTAYEHYRNVDP
YEDTHPPLGKIIIMLGIHLFGMNPFGWRFMGTLFGVLMVPILYIFLKNMFGKTAVAFCGA
ALFTFDFMHLVQTRIATIDSYGVFFILAMFFFLYRYLALPAGTPLYKCMPSLFLCGLMFG
LGVSSKWIVLYGGAGMALLYFLALFWKCREWPEDAYAPRRGLWVFGNILFCIFSFVIIPA
AIYILSYIPYATSNGVTDLKGLLEIVWENQTYMLTYHQGVMDEHPYSSRWYQWLLDIRPI
LYYMDNEPAGFTARFASFNNPLVTWGGLAAMVTVTVQTVRRACGKGLFILLGALSQFVPW
IIIGRTTFAYHYFPTIVFLCIAFAYIMNDLVESGRRWKPALYSVTGGAVALYALFYPALI
GYQVPVWFMKSFIKWFPSWPF

Enzyme Prediction     

No EC number prediction in MGYG000003600_00673.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT39	218	430	3.2e-56	0.9147982062780269

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1928	PMT1	9.35e-24	216	427	44	264	Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam16192	PMT_4TMC	1.43e-18	447	617	4	179	C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
pfam02366	PMT	1.99e-13	218	425	19	235	Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG4346	COG4346	7.52e-12	232	578	122	420	Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].
pfam13231	PMT_2	8.22e-11	245	383	2	131	Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ANU42918.1	3.72e-227	7	621	13	653
QQR07704.1	3.72e-227	7	621	13	653
QIA32159.1	5.27e-226	7	621	9	649
ALP95330.1	1.00e-207	9	621	25	752
QBB67038.1	1.00e-207	9	621	25	752

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8NRZ6	1.13e-24	196	619	56	519	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1
P9WN04	2.10e-22	202	619	71	521	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05	2.10e-22	202	619	71	521	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
L8F4Z2	4.79e-21	222	619	67	515	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000043	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
7	29
64	83
264	286
315	337
344	363
367	386
403	425
502	519
526	543
548	567
580	602