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CAZyme Information: MGYG000003630_01047
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | F082 sp900771045 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; F082; F082; F082 sp900771045 | |||||||||||
| CAZyme ID | MGYG000003630_01047 | |||||||||||
| CAZy Family | GT4 | |||||||||||
| CAZyme Description | Bifunctional protein GlmU | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 2183; End: 4006 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd06915 | NTP_transferase_WcbM_like | 5.14e-83 | 4 | 227 | 1 | 223 | WcbM_like is a subfamily of nucleotidyl transferases. WcbM protein of Burkholderia mallei is involved in the biosynthesis, export or translocation of capsule. It is a subfamily of nucleotidyl transferases that transfer nucleotides onto phosphosugars. |
| COG1208 | GCD1 | 5.41e-54 | 3 | 248 | 3 | 252 | NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]. |
| cd04181 | NTP_transferase | 2.91e-51 | 4 | 218 | 1 | 217 | NTP_transferases catalyze the transfer of nucleotides onto phosphosugars. Nucleotidyltransferases transfer nucleotides onto phosphosugars. The enzyme family includes Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase. The products are activated sugars that are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. |
| cd03822 | GT4_mannosyltransferase-like | 8.14e-46 | 236 | 601 | 1 | 357 | mannosyltransferases of glycosyltransferase family 4 and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides. |
| cd03801 | GT4_PimA-like | 9.98e-34 | 236 | 606 | 1 | 364 | phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BBE19260.1 | 1.06e-153 | 232 | 606 | 1 | 373 |
| AHW59699.1 | 2.21e-145 | 233 | 606 | 4 | 378 |
| ASZ13513.1 | 1.23e-142 | 234 | 606 | 5 | 376 |
| ADQ79882.1 | 1.40e-141 | 235 | 603 | 1 | 369 |
| QJX45595.1 | 1.45e-141 | 235 | 606 | 1 | 372 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6JQ8_A | 2.65e-45 | 1 | 230 | 1 | 224 | Crystalstructure of HddC from Yersinia pseudotuberculosis complexed with GMP-PN [Yersinia pseudotuberculosis] |
| 5XHW_A | 9.83e-44 | 2 | 230 | 14 | 236 | Crystalstructure of HddC from Yersinia pseudotuberculosis [Yersinia pseudotuberculosis] |
| 7X8J_A | 9.49e-19 | 5 | 223 | 6 | 228 | ChainA, Mannose-1-phosphate guanylyltransferase 1 [Arabidopsis thaliana],7X8J_B Chain B, Mannose-1-phosphate guanylyltransferase 1 [Arabidopsis thaliana],7X8K_A Chain A, Mannose-1-phosphate guanylyltransferase 1 [Arabidopsis thaliana],7X8K_B Chain B, Mannose-1-phosphate guanylyltransferase 1 [Arabidopsis thaliana],7X8K_C Chain C, Mannose-1-phosphate guanylyltransferase 1 [Arabidopsis thaliana],7X8K_D Chain D, Mannose-1-phosphate guanylyltransferase 1 [Arabidopsis thaliana] |
| 7D72_E | 2.24e-14 | 5 | 223 | 4 | 225 | ChainE, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_F Chain F, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_G Chain G, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_H Chain H, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_I Chain I, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_J Chain J, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_K Chain K, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D72_L Chain L, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_E Chain E, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_F Chain F, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_G Chain G, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_H Chain H, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_I Chain I, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_J Chain J, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_K Chain K, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D73_L Chain L, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_E Chain E, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_F Chain F, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_G Chain G, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_H Chain H, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_I Chain I, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_J Chain J, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_K Chain K, Mannose-1-phosphate guanyltransferase beta [Homo sapiens],7D74_L Chain L, Mannose-1-phosphate guanyltransferase beta [Homo sapiens] |
| 1JYL_A | 7.74e-09 | 5 | 70 | 29 | 93 | CatalyticMechanism of CTP:phosphocholine Cytidylyltransferase from Streptococcus pneumoniae (LicC) [Streptococcus pneumoniae],1JYL_B Catalytic Mechanism of CTP:phosphocholine Cytidylyltransferase from Streptococcus pneumoniae (LicC) [Streptococcus pneumoniae],1JYL_C Catalytic Mechanism of CTP:phosphocholine Cytidylyltransferase from Streptococcus pneumoniae (LicC) [Streptococcus pneumoniae],1JYL_D Catalytic Mechanism of CTP:phosphocholine Cytidylyltransferase from Streptococcus pneumoniae (LicC) [Streptococcus pneumoniae] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9AGY6 | 2.29e-60 | 3 | 229 | 2 | 225 | D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase OS=Aneurinibacillus thermoaerophilus OX=143495 GN=hddC PE=1 SV=1 |
| Q0P8J1 | 9.16e-50 | 3 | 224 | 2 | 215 | D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) OX=192222 GN=hddC PE=1 SV=1 |
| Q6BN12 | 8.94e-21 | 5 | 223 | 4 | 226 | Mannose-1-phosphate guanyltransferase OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=MPG1 PE=3 SV=1 |
| Q6CCU3 | 4.00e-20 | 5 | 249 | 4 | 254 | Mannose-1-phosphate guanyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=MPG1 PE=3 SV=1 |
| Q9P8N0 | 5.44e-20 | 5 | 249 | 4 | 255 | Mannose-1-phosphate guanyltransferase OS=Pichia angusta OX=870730 GN=MPG1 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000087 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |