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CAZyme Information: MGYG000003684_01021

You are here: Home > Sequence: MGYG000003684_01021

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eisenbergiella massiliensis
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella massiliensis
CAZyme ID MGYG000003684_01021
CAZy Family GH129
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
640 MGYG000003684_2|CGC12 72828.95 4.7117
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003684 6691925 Isolate China Asia
Gene Location Start: 569583;  End: 571505  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.49

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH129 5 638 1e-201 0.9498381877022654

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14244 GH_101_like 2.53e-101 291 572 1 287
Endo-a-N-acetylgalactosaminidase and related glcyosyl hydrolases. This family contains the enzymatically active domain of cell surface proteins that specifically cleave Gal-beta-1,3-GalNAc-alpha-Ser/Thr (T-antigen, galacto-N-biose), the core 1 type O-linked glycan common to mucin glycoproteins (EC:3.2.1.97). It has been classified as glycosyl hydrolase family 101 in the Cazy resource. Virulence of pathogenic organisms such as the Gram-positive Streptococcus pneumoniae and other commensal human bacteria is largely determined by their ability to degrade host glycoproteins and to metabolize the resultant carbohydrates.
pfam11308 Glyco_hydro_129 1.09e-14 317 617 2 323
Glycosyl hydrolases related to GH101 family, GH129. This family of bacterial and lower eukaryote glycosyl hydrolases is related to CAZy family GH129,and distantly to GH101, and is made up of sub-families GHL1-GHL3.
pfam12905 Glyco_hydro_101 3.20e-08 322 446 47 178
Endo-alpha-N-acetylgalactosaminidase. Virulence of pathogenic organisms such as the Gram-positive Streptococcus pneumoniae is largely determined by the ability to degrade host glycoproteins and to metabolize the resultant carbohydrates. This family is the enzymatic region, EC:3.2.1.97, of the cell surface proteins that specifically cleave Gal-beta-1,3-GalNAc-alpha-Ser/Thr (T-antigen, galacto-N-biose), the core 1 type O-linked glycan common to mucin glycoproteins. This reaction is exemplified by the S. pneumoniae protein Endo-alpha-N-acetylgalactosaminidase, where Asp764 is the catalytic nucleophile-base and Glu796 the catalytic proton donor.
pfam18952 DUF5696 1.89e-07 229 365 198 322
Family of unknown function (DUF5696). This is a family of unknown function with some overlap with clan family members of CL0058.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUO33311.1 1.81e-292 6 636 6 627
QBF72900.1 6.38e-286 11 637 11 628
QRO36270.1 6.38e-286 11 637 11 628
SET52246.1 3.22e-270 11 638 11 628
ADL03610.1 7.28e-266 11 640 11 630

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5WZN_A 8.59e-249 1 637 1 629
Alpha-N-acetylgalactosaminidaseNagBb from Bifidobacterium bifidum - GalNAc complex [Bifidobacterium bifidum],5WZN_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - GalNAc complex [Bifidobacterium bifidum],5WZP_A Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free [Bifidobacterium bifidum],5WZP_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free [Bifidobacterium bifidum],5WZR_A Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - Gal-NHAc-DNJ complex [Bifidobacterium bifidum],5WZR_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - Gal-NHAc-DNJ complex [Bifidobacterium bifidum]
5WZQ_A 4.94e-243 1 637 1 629
Alpha-N-acetylgalactosaminidaseNagBb from Bifidobacterium bifidum - quadruple mutant [Bifidobacterium bifidum],5WZQ_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - quadruple mutant [Bifidobacterium bifidum]
5OPQ_A 3.27e-18 154 630 204 655
A3,6-anhydro-D-galactosidase produced by Zobellia galactanivorans. This is an exo-lytic enzyme that hydrolyzes terminal 3,6-anhydro-D-galactose from the non-reducing end of carrageenan oligosaccharides. [Zobellia galactanivorans],5OPQ_B A 3,6-anhydro-D-galactosidase produced by Zobellia galactanivorans. This is an exo-lytic enzyme that hydrolyzes terminal 3,6-anhydro-D-galactose from the non-reducing end of carrageenan oligosaccharides. [Zobellia galactanivorans],5OPQ_C A 3,6-anhydro-D-galactosidase produced by Zobellia galactanivorans. This is an exo-lytic enzyme that hydrolyzes terminal 3,6-anhydro-D-galactose from the non-reducing end of carrageenan oligosaccharides. [Zobellia galactanivorans],5OPQ_D A 3,6-anhydro-D-galactosidase produced by Zobellia galactanivorans. This is an exo-lytic enzyme that hydrolyzes terminal 3,6-anhydro-D-galactose from the non-reducing end of carrageenan oligosaccharides. [Zobellia galactanivorans]
6QEP_A 7.03e-06 305 445 320 458
EngBFDARPin Fusion 4b H14 [Bifidobacterium longum]
6QEV_B 7.03e-06 305 445 320 458
EngBFDARPin Fusion 4b B6 [Bifidobacterium longum]

Swiss-Prot Hits      help

has no Swissprot hit.

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000028 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003684_01021.