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CAZyme Information: MGYG000003701_01028
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Parabacteroides sp003480915 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides sp003480915 | |||||||||||
| CAZyme ID | MGYG000003701_01028 | |||||||||||
| CAZy Family | GH33 | |||||||||||
| CAZyme Description | N-acetylneuraminate epimerase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 62686; End: 66450 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH33 | 33 | 412 | 2.3e-83 | 0.9415204678362573 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11495 | SLC5sbd_NIS-like_u3 | 0.0 | 761 | 1233 | 1 | 473 | uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain. Proteins belonging to the same subfamily as this uncharacterized subgroup include i) NIS, which transports I-, and other anions including ClO4-, SCN-, and Br-, ii) SMVT, which transports biotin, pantothenic acid and lipoate, and iii) the Na(+)/monocarboxylate cotransporters SMCT1 and 2. SMCT1 is a high-affinity transporter while SMCT2 is a low-affinity transporter. This subgroup belongs to the solute carrier 5 (SLC5) transporter family. |
| cd10326 | SLC5sbd_NIS-like | 1.57e-104 | 765 | 1231 | 1 | 472 | Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain. NIS (product of the SLC5A5 gene) transports I-, and other anions including ClO4-, SCN-, and Br-. SMVT (product of the SLC5A6 gene) transports biotin, pantothenic acid and lipoate. This subfamily also includes SMCT1 and 2. SMCT1(the product of the SLC5A8 gene) is a high-affinity transporter of various monocarboxylates including lactate and pyruvate, short-chain fatty acids, ketone bodies, nicotinate and its structural analogs, pyroglutamate, benzoate and its derivatives, and iodide. SMCT2 (product of the SLC5A12 gene) is a low-affinity transporter for short-chain fatty acids, lactate, pyruvate, and nicotinate. This subfamily belongs to the solute carrier 5 (SLC5) transporter family. |
| cd11494 | SLC5sbd_NIS-like_u2 | 1.60e-100 | 765 | 1231 | 2 | 473 | uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain. Proteins belonging to the same subfamily as this uncharacterized subgroup include i) NIS, which transports I-, and other anions including ClO4-, SCN-, and Br-, ii) SMVT, which transports biotin, pantothenic acid and lipoate, and iii) the Na(+)/monocarboxylate cotransporters, SMCT1 and 2. SMCT1 is a high-affinity transporter while SMCT2 is a low-affinity transporter. This subgroup belongs to the solute carrier 5 (SLC5) transporter family. |
| cd11492 | SLC5sbd_NIS-SMVT | 1.03e-91 | 764 | 1204 | 1 | 445 | Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain. NIS (encoded by the SLC5A5 gene) transports I-, and other anions including ClO4-, SCN-, and Br-. SMVT (encoded by the SLC5A6 gene) transports biotin, pantothenic acid and lipoate. This subfamily also includes SMCT1 and -2. SMCT1(encoded by the SLC5A8 gene) is a high-affinity transporter of various monocarboxylates including lactate and pyruvate, short-chain fatty acids, ketone bodies, nicotinate and its structural analogs, pyroglutamate, benzoate and its derivatives, and iodide. SMCT2 (encoded by the SLC5A12 gene) is a low-affinity transporter for short-chain fatty acids, lactate, pyruvate, and nicotinate. This subgroup belongs to the solute carrier 5 (SLC5) transporter family. |
| cd11493 | SLC5sbd_NIS-like_u1 | 3.02e-91 | 765 | 1231 | 1 | 479 | uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain. Proteins belonging to the same subfamily as this uncharacterized subgroup include i) NIS, which transports I-, and other anions including ClO4-, SCN-, and Br-, ii) SMVT, which transports biotin, pantothenic acid and lipoate, and iii) the Na(+)/monocarboxylate cotransporters SMCT1 and 2. SMCT1 is a high-affinity transporter while SMCT2 is a low-affinity transporter. This subgroup belongs to the solute carrier 5 (SLC5) transporter family. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QGY44271.1 | 5.16e-167 | 31 | 427 | 42 | 440 |
| QEC52363.1 | 3.15e-100 | 9 | 413 | 10 | 412 |
| QEH41786.1 | 1.32e-63 | 9 | 414 | 7 | 359 |
| SDS88269.1 | 6.54e-61 | 26 | 436 | 65 | 419 |
| BCJ69463.1 | 3.70e-60 | 31 | 406 | 52 | 372 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5NVA_A | 3.23e-90 | 761 | 1241 | 6 | 487 | Substrate-boundoutward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site [Proteus mirabilis HI4320] |
| 5NV9_A | 2.29e-85 | 761 | 1241 | 6 | 487 | Substrate-boundoutward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site [Proteus mirabilis HI4320] |
| 7SL9_A | 2.31e-40 | 755 | 1196 | 2 | 448 | ChainA, Sodium-coupled monocarboxylate transporter 1 [Homo sapiens] |
| 2XQ2_A | 3.55e-30 | 762 | 1197 | 9 | 463 | Structureof the K294A mutant of vSGLT [Vibrio parahaemolyticus] |
| 1EUR_A | 1.90e-29 | 27 | 409 | 7 | 346 | Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q5E733 | 4.88e-91 | 757 | 1254 | 2 | 499 | N-acetylneuraminate transporter OS=Aliivibrio fischeri (strain ATCC 700601 / ES114) OX=312309 GN=nanT PE=3 SV=1 |
| Q9Y289 | 2.31e-44 | 761 | 1200 | 24 | 466 | Sodium-dependent multivitamin transporter OS=Homo sapiens OX=9606 GN=SLC5A6 PE=1 SV=2 |
| P83740 | 2.84e-43 | 765 | 1197 | 8 | 448 | Putative sodium-dependent multivitamin transporter OS=Drosophila melanogaster OX=7227 GN=CG32669 PE=2 SV=1 |
| Q9XT77 | 7.88e-43 | 755 | 1200 | 18 | 466 | Sodium-dependent multivitamin transporter OS=Oryctolagus cuniculus OX=9986 GN=SLC5A6 PE=2 SV=1 |
| Q49B93 | 1.13e-42 | 765 | 1215 | 10 | 459 | Sodium-coupled monocarboxylate transporter 2 OS=Mus musculus OX=10090 GN=Slc5a12 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000058 | 0.053646 | 0.946266 | 0.000017 | 0.000023 | 0.000022 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 759 | 781 |
| 801 | 823 |
| 833 | 855 |
| 878 | 900 |
| 915 | 937 |
| 942 | 964 |
| 984 | 1006 |
| 1033 | 1055 |
| 1070 | 1092 |
| 1128 | 1150 |
| 1160 | 1182 |
| 1189 | 1208 |
| 1212 | 1234 |