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CAZyme Information: MGYG000003716_00311

You are here: Home > Sequence: MGYG000003716_00311

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Lawsonella;
CAZyme ID MGYG000003716_00311
CAZy Family GT53
CAZyme Description putative arabinosyltransferase B
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1145 MGYG000003716_28|CGC1 125256.5 9.5864
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003716 1367201 MAG Canada North America
Gene Location Start: 5619;  End: 9056  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT53 45 1143 0 0.9971401334604385

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04602 Arabinose_trans 0.0 235 704 1 459
Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
pfam14896 Arabino_trans_C 0.0 743 1143 1 384
EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate.
pfam17689 Arabino_trans_N 1.14e-42 71 231 1 155
Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALE19641.1 0.0 1 1145 1 1145
ALE34620.1 0.0 39 1145 2 1108
VHO00484.1 0.0 59 1145 1 1087
QYB01362.1 0.0 45 1144 28 1103
QSE81683.1 0.0 45 1144 28 1103

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7BWR_A 1.77e-267 43 1144 22 1080
Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155]
6X0O_A 2.93e-267 43 1144 22 1080
Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155]
7BVC_B 3.12e-267 43 1144 22 1080
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155]
7BVE_A 9.40e-265 43 1144 11 1073
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155]
7BVH_A 2.32e-264 43 1144 24 1086
Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q50395 1.94e-266 43 1144 22 1080
Probable arabinosyltransferase B OS=Mycolicibacterium smegmatis OX=1772 GN=embB PE=3 SV=3
P71486 5.00e-262 43 1144 9 1063
Probable arabinosyltransferase B OS=Mycobacterium avium OX=1764 GN=embB PE=3 SV=1
P9WNL7 7.05e-262 21 1145 2 1097
Probable arabinosyltransferase B OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embB PE=1 SV=1
P9WNL6 7.05e-262 21 1145 2 1097
Probable arabinosyltransferase B OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embB PE=3 SV=1
Q7TVN3 1.41e-261 21 1145 2 1097
Probable arabinosyltransferase B OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999935 0.000071 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
46 68
242 264
285 307
363 385
397 414
452 474
487 509
556 573
580 602
612 634
641 663
678 700
721 743