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CAZyme Information: MGYG000003769_00661

You are here: Home > Sequence: MGYG000003769_00661

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium;
CAZyme ID MGYG000003769_00661
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
844 MGYG000003769_4|CGC3 99508.57 5.0239
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003769 4856301 MAG Canada North America
Gene Location Start: 90060;  End: 92594  Strand: -

Full Sequence      Download help

MIYHSLNDTW  NFKKLTGEDW  YDVEIPGSVL  KGLLKYNVIP  DPYYRTNEYL  VKEELRYDYV60
FVRHFDLDEA  IRNEECIEFV  FDGIDTLAEI  FLNDIFLEST  NNMHRTYRIS  CKEYLQAKNE120
LKIIIRSPIT  YIESYQWEEG  KEITYIPSGG  MKGNQYLRKA  HSMFGWDWGA  QLPDMGIFRD180
VSLVAYSEIK  LGDVRFTQIH  NNNKVRLEIV  VAYDLLESKG  EEYVIQTKVY  DPQGNKLWNH240
TDEIMRNTKE  AMGSTKEAVR  YSKEVEQTVL  IDEPKLWWPN  GFGEQALYEV  EVSIVCKRNQ300
KVYETKKYRI  GLRTIVISQE  KDMWGSEFAF  VINDVKIFAK  GANYIPEDCI  YSDITYERIK360
YLITSCIRAN  YNCIRVWGGG  YYPSDAFYDL  CDEYGLIVWQ  DLMFACNIYD  LSDEFAETIV420
AELKDNVTRL  RHHASLGLWC  GNNEIESAWH  QWGNFQSHSA  KLRADYIIQF  EYLLPKAVKE480
CDPHTFYWPS  SPSSGGCFDH  PDDENRGDVH  YWEVWHGRKP  FSDYQKHYFR  FCSEFGFQSF540
PEFRTIESFA  VEEDFNIFSK  VMESHQKNEA  ANGAILYYIS  EQFRYPKDFK  KLIYISQILQ600
GLAIKSGVEH  FRRNRGRCMG  SLYWQLNDNW  PVASWSSIDY  YGRWKALHYM  AKKFYGQTAG660
SIVRDETRIK  VFVANENLNG  VYVTARIALK  TMNLEVLKEE  THNIFVEKQS  SIKVAELDYC720
KELKGKEEEV  FVEASFYFPD  GSKSTEYMDF  VPFKYLKLQK  PNIRMQIKES  DESYMYYFKT780
DCYAPFVMLS  IANVDVIWSD  NFFSLSDEDE  TVIILRKSDI  WGGKEVTLEY  LYENTHFCSL840
YDSY844

Enzyme Prediction      help

No EC number prediction in MGYG000003769_00661.

CAZyme Signature Domains help

Created with Snap42841261682112532953373794224645065485906336757177598014740GH2
Family Start End Evalue family coverage
GH2 4 740 1e-103 0.7207446808510638

CDD Domains      download full data without filtering help

Created with Snap42841261682112532953373794224645065485906336757177598014655LacZ63444ebgA760842Ig_mannosidase193313Glyco_hydro_2174398lacZ
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 1.18e-92 4 655 13 629
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 2.42e-11 63 444 115 449
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam17753 Ig_mannosidase 9.66e-11 760 842 1 78
Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.
pfam00703 Glyco_hydro_2 1.35e-10 193 313 5 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK09525 lacZ 1.29e-06 174 398 202 410
beta-galactosidase.

CAZyme Hits      help

Created with Snap42841261682112532953373794224645065485906336757177598016824CBL20579.1|GH26820QCU02115.1|GH26809CBL13897.1|GH26809VCV23589.1|GH26809CBL08662.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
CBL20579.1 6.01e-311 6 824 6 822
QCU02115.1 5.19e-306 6 820 6 804
CBL13897.1 1.13e-273 6 809 16 829
VCV23589.1 3.58e-273 6 809 9 822
CBL08662.1 3.58e-273 6 809 9 822

PDB Hits      download full data without filtering help

Created with Snap428412616821125329533737942246450654859063367571775980168262VJX_A68262JE8_A68267OP6_A68262WBK_A58186BYE_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2VJX_A 3.77e-142 6 826 11 827
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A 3.98e-142 6 826 13 829
Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A 4.09e-142 6 826 13 829
ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A 1.07e-141 6 826 11 827
Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
6BYE_A 3.30e-140 5 818 7 836
Crystalstructure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri in complex with mannose [Xanthomonas citri pv. citri str. 306],6BYE_B Crystal structure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri in complex with mannose [Xanthomonas citri pv. citri str. 306]

Swiss-Prot Hits      download full data without filtering help

Created with Snap42841261682112532953373794224645065485906336757177598015844sp|Q29444|MANBA_BOVIN5844sp|Q95327|MANBA_CAPHI4803sp|Q8K2I4|MANBA_MOUSE4844sp|O00462|MANBA_HUMAN4813sp|Q4FZV0|MANBA_RAT
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q29444 6.21e-112 5 844 24 879
Beta-mannosidase OS=Bos taurus OX=9913 GN=MANBA PE=1 SV=1
Q95327 8.66e-112 5 844 24 879
Beta-mannosidase OS=Capra hircus OX=9925 GN=MANBA PE=1 SV=1
Q8K2I4 4.09e-100 4 803 23 844
Beta-mannosidase OS=Mus musculus OX=10090 GN=Manba PE=1 SV=1
O00462 4.12e-99 4 844 23 879
Beta-mannosidase OS=Homo sapiens OX=9606 GN=MANBA PE=1 SV=3
Q4FZV0 4.28e-95 4 813 23 856
Beta-mannosidase OS=Rattus norvegicus OX=10116 GN=Manba PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000073 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003769_00661.