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CAZyme Information: MGYG000003805_00138

You are here: Home > Sequence: MGYG000003805_00138

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium;
CAZyme ID MGYG000003805_00138
CAZy Family GT53
CAZyme Description putative arabinosyltransferase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1129 122670.19 4.9088
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003805 2110817 MAG Canada North America
Gene Location Start: 417;  End: 3806  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT53 36 1124 0 0.9933269780743565

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04602 Arabinose_trans 0.0 220 677 1 458
Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
pfam14896 Arabino_trans_C 1.36e-174 727 1124 1 384
EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate.
pfam17689 Arabino_trans_N 5.38e-47 58 216 1 155
Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AQQ14089.1 0.0 1 1128 1 1161
QQU85087.1 0.0 32 1128 6 1102
AKV59977.1 0.0 32 1128 8 1104
SNV53280.1 0.0 32 1129 13 1100
AIJ32602.1 0.0 32 1129 13 1100

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6X0O_A 6.07e-259 38 1129 30 1084
Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155]
7BWR_A 7.36e-259 38 1126 30 1081
Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155]
7BVC_B 1.29e-258 38 1126 30 1081
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155]
7BVE_A 2.20e-258 38 1125 19 1073
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155]
7BVH_A 5.40e-258 38 1125 32 1086
Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q50395 1.43e-258 38 1126 30 1081
Probable arabinosyltransferase B OS=Mycolicibacterium smegmatis OX=1772 GN=embB PE=3 SV=3
Q50393 6.17e-255 38 1125 19 1073
Probable arabinosyltransferase C OS=Mycolicibacterium smegmatis OX=1772 GN=embC PE=3 SV=2
Q7TVN4 4.36e-248 38 1124 33 1092
Probable arabinosyltransferase C OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embC PE=3 SV=1
P9WNL5 1.23e-247 38 1124 33 1092
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embC PE=1 SV=1
P9WNL4 1.73e-247 38 1124 33 1092
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embC PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999896 0.000138 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
33 55
222 244
332 354
366 385
426 448
461 483
525 547
559 576
586 608
615 637
652 674
708 730