CAZyme Information: MGYG000003805_00639

Basic Information

• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium
• CAZyme ID: MGYG000003805_00639
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
417		42646.05	4.3383

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003805	2110817	MAG	Canada	North America

• Gene Location: Start: 7924; End: 9177 Strand: +

Full Sequence      

MRAACVVRAVPVVTSAVTAAALMCASLSGCAGDGGLQEPSTTQESAAASSTTAGAVSSSS
SASLSPSPVAPVTGLNPAEMGSAQARVPADVRGKVASLMVVGVTDYEQAKAALEQGVGGL
IIPSWADSGLLTEPGHDINALREQYPRPFAVAIDFEGGRVQRHTNVLGDFMAPRALAATP
DEVIQGTGYDIGRSLREHGVNVDYAPVVDLDVSDLDIVGDRAFGGDPAEVTRVAALFAQG
LIDAGVTPTFKHFPGHGRASGDTHHALAVTPPLEDVRGLDMLPYGPLAQQFPGGVTSVMM
GHMIVPGLGPEGVPSSLNPEAYRILREGDYPGGVPFGGVVVTDDLSGMRGILDYAPTPEA
VKRAIAAGADQALWSSGVDVAEIIGYVTAAVESGELPLARVEEAAIRGQQQLIDAGL

Enzyme Prediction     

No EC number prediction in MGYG000003805_00639.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	147	373	3.9e-38	0.9537037037037037

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	1.67e-50	91	407	3	307	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	5.71e-46	91	407	2	312	Glycosyl hydrolase family 3 N terminal domain.
PRK05337	PRK05337	1.26e-29	117	306	26	218	beta-hexosaminidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SNV84715.1	5.49e-183	83	417	70	402
AIL97614.1	4.50e-181	13	417	3	398
AQQ16199.1	2.67e-179	99	417	1	317
AKV60024.1	3.12e-179	90	407	40	355
QQU84364.1	3.47e-179	90	407	43	358

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5IOB_A	7.62e-109	64	409	4	344	Crystalstructure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_B Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_C Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_D Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_E Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_F Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_G Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_H Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032]
4YYF_A	5.03e-73	62	408	22	360	ChainA, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_B Chain B, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_C Chain C, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155]
6GFV_A	2.08e-72	92	407	19	332	Mtuberculosis LpqI [Mycobacterium tuberculosis H37Rv],6GFV_B M tuberculosis LpqI [Mycobacterium tuberculosis H37Rv]
6K5J_A	2.44e-34	91	416	13	345	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
5G1M_A	3.65e-30	151	373	79	293	Crystalstructure of NagZ from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G1M_B Crystal structure of NagZ from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G2M_A Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine [Pseudomonas aeruginosa PAO1],5G2M_B Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine [Pseudomonas aeruginosa PAO1],5G3R_A Crystal Structure Of Nagz From Pseudomonas Aeruginosa In Complex With N-acetylglucosamine And L-ala-1,6-anhydromurnac [Pseudomonas aeruginosa PAO1],5G3R_B Crystal Structure Of Nagz From Pseudomonas Aeruginosa In Complex With N-acetylglucosamine And L-ala-1,6-anhydromurnac [Pseudomonas aeruginosa PAO1],5G5K_A Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1],5G5K_B Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
L7N6B0	4.14e-71	92	407	62	375	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
A0A0H3M1P5	1.16e-70	92	407	62	375	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1
Q2KXM7	1.01e-29	107	382	26	300	Beta-hexosaminidase OS=Bordetella avium (strain 197N) OX=360910 GN=nagZ PE=3 SV=1
Q9HZK0	1.39e-29	151	373	59	273	Beta-hexosaminidase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=nagZ PE=1 SV=1
Q02PG9	1.39e-29	151	373	59	273	Beta-hexosaminidase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) OX=208963 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000023	0.002370	0.997600	0.000001	0.000005	0.000001

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003805_00639.