CAZyme Information: MGYG000003806_00041

Basic Information

• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium
• CAZyme ID: MGYG000003806_00041
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
349	MGYG000003806_1|CGC1	36073.84	3.9027

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003806	2539854	MAG	Canada	North America

• Gene Location: Start: 49262; End: 50311 Strand: -

Full Sequence      

MPALLLSATCALSACSEEPVLSDAPPSETSAAASSAASGDAAEHDAAPEDVRARAAAKLM
PPALNYEDARVKLEAGVGGLFIPSWADPELLSDGPRGVNALREEMGRDFEVSIDFEGGRV
QRFSEILGDYPSPQAMAEGHSPDEVEALATEIGQSLRAHGVTVDFAPVLDVDGGDLEVVG
DRAFSTAPQAAGEYGAAFARGLQAAGVKAVFKHFPGHGRASGDTHLGEAVTPPLEELYGH
EFVPFHTAIPQAPDAALMMGHLVVPGLGDEPASLNPQAYQLAREELGFEGTIYTDDLGGM
ASISDSFSVPEAVAAALAAGADMPLWSTDDDINAVIDAAADVVDQQEGD

Enzyme Prediction     

No EC number prediction in MGYG000003806_00041.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	111	325	2.7e-45	0.9351851851851852

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	8.45e-65	59	349	12	302	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	2.06e-49	61	344	16	297	Glycosyl hydrolase family 3 N terminal domain.
PRK05337	PRK05337	8.57e-46	77	301	26	254	beta-hexosaminidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QQU96255.1	1.80e-217	1	349	5	353
QQU94378.1	9.00e-216	1	349	1	345
ACP33941.1	1.04e-215	1	349	5	349
QRP61872.1	7.62e-203	3	349	7	363
AJI79939.1	6.72e-202	3	347	7	359

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5IOB_A	5.45e-91	49	337	26	320	Crystalstructure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_B Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_C Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_D Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_E Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_F Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_G Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_H Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032]
4YYF_A	1.30e-66	52	337	42	332	ChainA, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_B Chain B, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_C Chain C, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155]
6GFV_A	7.55e-63	51	337	28	310	Mtuberculosis LpqI [Mycobacterium tuberculosis H37Rv],6GFV_B M tuberculosis LpqI [Mycobacterium tuberculosis H37Rv]
5G1M_A	7.79e-33	64	329	34	297	Crystalstructure of NagZ from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G1M_B Crystal structure of NagZ from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G2M_A Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine [Pseudomonas aeruginosa PAO1],5G2M_B Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine [Pseudomonas aeruginosa PAO1],5G3R_A Crystal Structure Of Nagz From Pseudomonas Aeruginosa In Complex With N-acetylglucosamine And L-ala-1,6-anhydromurnac [Pseudomonas aeruginosa PAO1],5G3R_B Crystal Structure Of Nagz From Pseudomonas Aeruginosa In Complex With N-acetylglucosamine And L-ala-1,6-anhydromurnac [Pseudomonas aeruginosa PAO1],5G5K_A Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1],5G5K_B Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1]
5G5U_A	1.49e-31	64	329	34	297	Crystalstructure of NagZ H174A mutant from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G5U_B Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G6T_A Crystal structure of Zn-containing NagZ H174A mutant from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G6T_B Crystal structure of Zn-containing NagZ H174A mutant from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5LY7_A Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1],5LY7_B Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
L7N6B0	1.39e-61	51	337	71	353	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
A0A0H3M1P5	3.86e-61	51	337	71	353	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1
B2FPW9	1.75e-40	100	325	46	276	Beta-hexosaminidase OS=Stenotrophomonas maltophilia (strain K279a) OX=522373 GN=nagZ PE=3 SV=1
B4SRK3	2.45e-40	100	325	46	276	Beta-hexosaminidase OS=Stenotrophomonas maltophilia (strain R551-3) OX=391008 GN=nagZ PE=3 SV=1
Q82SJ8	1.87e-37	67	331	17	287	Beta-hexosaminidase OS=Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) OX=228410 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000002	0.000112	0.999905	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003806_00041.