CAZyme Information: MGYG000003812_01558

Basic Information

• Species: Prevotella colorans
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella colorans
• CAZyme ID: MGYG000003812_01558
• CAZy Family: GT51
• CAZyme Description: Monofunctional biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
143		16039.78	9.6419

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003812	2316911	MAG	Canada	North America

• Gene Location: Start: 32; End: 463 Strand: -

Full Sequence      

MQKLFHLSIMRKCIIKSLWIFSFFIVVTIAILFFLIWYGIIGYSPDIEHLQNPINKSASL
IYSADGKVIGTYNLDRANRIPVSYSKLSPHLVHALVATEDERFYEHSGIDFIALARAVIK
RGILGQESAGGGSTITQQLAKQL

Enzyme Prediction     

No EC number prediction in MGYG000003812_01558.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	65	143	3.6e-24	0.423728813559322

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG5009	MrcA	3.09e-34	10	143	1	130	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
pfam00912	Transgly	2.11e-31	65	143	1	76	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG0744	MrcB	2.41e-31	10	143	8	140	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
PRK11636	mrcA	1.48e-21	15	141	4	127	penicillin-binding protein 1a; Provisional
PRK00056	mtgA	9.09e-18	82	143	63	123	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AGB28102.1	1.15e-62	10	143	1	134
QYR10397.1	5.30e-53	10	143	1	134
QUB54911.1	1.91e-52	10	143	1	134
ATV39520.1	2.64e-52	10	143	1	134
ATV53834.1	2.64e-52	10	143	1	134

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5U2G_A	3.44e-15	45	141	8	101	2.6Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20],5U2G_B 2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae [Haemophilus influenzae Rd KW20]
3UDF_A	4.02e-14	61	141	23	100	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]
3NB6_A	5.26e-13	66	143	9	83	Crystalstructure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin [Aquifex aeolicus]
2OQO_A	1.99e-12	66	143	9	83	Crystalstructure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis [Aquifex aeolicus VF5],3D3H_A Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A [Aquifex aeolicus],3NB7_A Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin [Aquifex aeolicus]
2JE5_A	1.94e-11	45	142	19	116	StructuralAnd Mechanistic Basis Of Penicillin Binding Protein Inhibition By Lactivicins [Streptococcus pneumoniae R6],2JE5_B Structural And Mechanistic Basis Of Penicillin Binding Protein Inhibition By Lactivicins [Streptococcus pneumoniae R6]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q87AW7	3.36e-16	37	142	30	133	Penicillin-binding protein 1A OS=Xylella fastidiosa (strain Temecula1 / ATCC 700964) OX=183190 GN=mrcA PE=3 SV=1
Q9PGD4	8.50e-16	37	142	30	133	Penicillin-binding protein 1A OS=Xylella fastidiosa (strain 9a5c) OX=160492 GN=mrcA PE=3 SV=2
P02918	1.17e-15	45	141	34	127	Penicillin-binding protein 1A OS=Escherichia coli (strain K12) OX=83333 GN=mrcA PE=1 SV=1
O66874	3.94e-15	45	143	31	126	Penicillin-binding protein 1A OS=Aquifex aeolicus (strain VF5) OX=224324 GN=mrcA PE=1 SV=1
P31776	1.64e-13	49	141	28	116	Penicillin-binding protein 1A OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=mrcA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000020	0.000010	0.000000	0.000000	0.000000	0.000013

TMHMM  Annotations     

start	end
19	41