CAZyme Information: MGYG000003816_02225

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-485
• CAZyme ID: MGYG000003816_02225
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
777		87352.99	6.159

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003816	2849186	MAG	United States	North America

• Gene Location: Start: 751; End: 3084 Strand: +

Full Sequence      

MNSFKSIILSAATAAAVIISPPEAAAADGFTIERGTDLTVSLPSSRRPVLNSAVALLGRD
LRNVFGDTVAIVRKNGRIDIKIDPKAVKDVQGYRMEVTPDGRLAVTGHDSAGAAYALMEL
SRHIGVSPWEWWADAAPEARDSFSLPAGFVSSQAPDVEYRGIFINDEDWGLMPWSSSTHE
PGNKRGVIGAKTNERIFELMLRLRANYYWPAMHECTEPFFLTPDNREMAERFGIYVGGSH
CEPMASSTAVEWGRRGKGEYDYVGNSGNVYRFWEERVKDVAGQEIVYTLGMRGVHDGAMN
GAKTVEEQKAVLTRAIADQRGLLRKYVDKKVERVPQVFIPYKEVLDVYRAGLEVPEDVTL
MWCDDNYGYIRHFPTAEEAARKGGNGIYYHVSYWGRPHDYLWLSSLSPYLMWQQMKLAYD
KGIRKMWILNVGDIKPAEYQTELFMDMAWDIDAVAERGIRGNMEDFYAREFGQKAAGEIV
PMMDEYYRLASIRMPEFMGNTRTEERDRAYYNKVRDIAWSDRYVRDRIADYGALEEKADL
IAGEIPANRRDTYYQLVEYPVKAAAEMNKKMLFAQLARHGKADWSRSREAYDSIVALTKI
YNEGFSNGGKWKGIMDMRPRKLPVFNPVTPDTCQEPVSPDTRVIEARLHNSGNLIGHTGL
GHTGHAVEIPLGKTAEYTLPASRQDSVCVYLNFLPVHPVVDGGGLKAEVSYGGGAPQTID
YATQGRSEEWKENILNGRAVRRLVFPSPAAGKSADTTLRIKALTEGIILDWIEVERD

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	33	771	1.4e-209	0.9870875179340028

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	1.17e-180	153	497	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	7.03e-09	659	774	32	158	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
EDY97203.1	0.0	30	774	22	782
AII64660.1	0.0	30	774	21	779
QDM08765.1	0.0	30	774	21	777
ABR39833.1	0.0	30	774	21	777
QUT62833.1	0.0	30	774	21	777

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	1.89e-294	30	777	20	779	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4C90_A	2.90e-91	100	775	140	835	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PXQ_A	1.11e-87	103	618	115	627	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PUG_A	1.57e-87	103	618	116	628	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	3.13e-87	44	611	50	606	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000314	0.998983	0.000181	0.000175	0.000173	0.000153

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003816_02225.