logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000003834_00020

You are here: Home > Sequence: MGYG000003834_00020

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Eisenbergiella sp900550285
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella sp900550285
CAZyme ID MGYG000003834_00020
CAZy Family GH27
CAZyme Description Alpha-galactosidase A
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
376 MGYG000003834_1|CGC1 42598.59 4.6964
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003834 2806677 MAG United States North America
Gene Location Start: 23099;  End: 24229  Strand: +

Full Sequence      Download help

MVKLTPPMGW  NSWNTFGENI  SEQLIMETAD  AMVDEGLLEK  GYEYLVIDDC  WSLRERDENG60
RLVADPEKFP  HGMKAVADYV  HSKGLKFGMY  SCAGNLTCAG  YPGSFEHEFV  DAETFAEWGV120
DFLKYDYCYH  SPIIPGKYLY  RRMGLALENC  GRDILFSACS  WGADETHEWI  KETGASMWRS180
TGDIFDTWES  IKDLTKQQEK  LHPFNGVGCF  NDMDMLVVGM  YGKGNVGLAG  CTDVQYKTHY240
SIWALLGSPL  MIGCDIRNMN  QATKDILMNP  EMIAINQDPL  CRQPVRLTGI  WSGEDVVLYS300
RQLFNGDLAI  GLFNMSDKKT  TVNLNLDELG  LPLSTQRTLR  LKEVWTGEER  NVPNATLRRE360
LEPFDCAVYR  GKVVKL376

Enzyme Prediction      help

No EC number prediction in MGYG000003834_00020.

CAZyme Signature Domains help

Created with Snap1837567594112131150169188206225244263282300319338357100349GH27
Family Start End Evalue family coverage
GH27 100 349 7.9e-74 0.9868995633187773

CDD Domains      download full data without filtering help

Created with Snap18375675941121311501691882062252442632823003193383576278GH274369PLN028084369PLN022294356PLN026925278Melibiase_2
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14792 GH27 1.01e-147 6 278 1 271
glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
PLN02808 PLN02808 1.98e-111 4 369 30 381
alpha-galactosidase
PLN02229 PLN02229 2.76e-111 4 369 61 415
alpha-galactosidase
PLN02692 PLN02692 1.63e-101 4 356 54 395
alpha-galactosidase
pfam16499 Melibiase_2 3.27e-100 5 278 1 284
Alpha galactosidase A.

CAZyme Hits      help

Created with Snap18375675941121311501691882062252442632823003193383571376VCV24057.1|GH271375QAA34453.1|GH271375AEE96273.1|GH271375APO43919.1|GH274374AIQ40862.1|GH27
Hit ID E-Value Query Start Query End Hit Start Hit End
VCV24057.1 4.81e-228 1 376 1 376
QAA34453.1 9.34e-167 1 375 1 374
AEE96273.1 1.47e-161 1 375 1 376
APO43919.1 3.96e-159 1 375 6 387
AIQ40862.1 6.68e-159 4 374 14 392

PDB Hits      download full data without filtering help

Created with Snap183756759411213115016918820622524426328230031933835753691UAS_A43694NZJ_A53696F4C_B43694OGZ_A23453A5V_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
1UAS_A 7.21e-94 5 369 8 357
ChainA, alpha-galactosidase [Oryza sativa]
4NZJ_A 1.25e-91 4 369 98 471
Crystalstructure of a putative alpha-galactosidase (BF1418) from Bacteroides fragilis NCTC 9343 at 1.57 A resolution [Bacteroides fragilis NCTC 9343]
6F4C_B 1.22e-89 5 369 8 358
Nicotianabenthamiana alpha-galactosidase [Nicotiana benthamiana]
4OGZ_A 4.84e-87 4 369 98 470
Crystalstructure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343],4OGZ_B Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343]
3A5V_A 1.93e-82 2 345 5 364
Crystalstructure of alpha-galactosidase I from Mortierella vinacea [Umbelopsis vinacea]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375675941121311501691882062252442632823003193383575369sp|P14749|AGAL_CYATE5369sp|Q8VXZ7|AGAL3_ARATH2369sp|Q8RX86|AGAL2_ARATH4369sp|Q42656|AGAL_COFAR5369sp|Q9FXT4|AGAL_ORYSJ
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P14749 3.42e-98 5 369 55 405
Alpha-galactosidase OS=Cyamopsis tetragonoloba OX=3832 PE=1 SV=1
Q8VXZ7 1.91e-95 5 369 72 425
Alpha-galactosidase 3 OS=Arabidopsis thaliana OX=3702 GN=AGAL3 PE=1 SV=1
Q8RX86 2.82e-93 2 369 36 389
Alpha-galactosidase 2 OS=Arabidopsis thaliana OX=3702 GN=AGAL2 PE=1 SV=1
Q42656 1.30e-92 4 369 22 373
Alpha-galactosidase OS=Coffea arabica OX=13443 PE=1 SV=1
Q9FXT4 2.12e-92 5 369 63 412
Alpha-galactosidase OS=Oryza sativa subsp. japonica OX=39947 GN=Os10g0493600 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000064 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003834_00020.