CAZyme Information: MGYG000003844_00431

Basic Information

• Species: Ruminiclostridium_E sp900539195
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminiclostridium_E; Ruminiclostridium_E sp900539195
• CAZyme ID: MGYG000003844_00431
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
894		100341.71	4.6266

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003844	2672388	MAG	United States	North America

• Gene Location: Start: 172728; End: 175412 Strand: +

Full Sequence      

MINTIDISGKWELFISENNRTLLPDNYNDSIILPDTLSDAAKVAENKNRDEGYLTDKYTF
TGYAWFRRSLTVESDMTGLVSILTLERTRVSTLYIDGAEVGTCDSLCSTHRYDISSYMTA
GTHEIVIRVANVGYKTGGGHMTSPDTQTNWLGIVGKMNIEIYPKSYISDVRVIASADGSL
SVRGTASGADNAVVTATVTAPGGIRVLKANIIADGDTFESEFRLENAQLWDEFERNIYSL
ELRCGEDIFNTSFGFVTFSGNDRKLLVNGGESFLRGKHDGMIFPLTAYAPCDINDWKERL
KIAKSYGINHYRFHTCCPPDAAFTAADELGIYMEPELPFWGTIAAKGEDGYNEEEQDYLI
NEGIRIIKEFSHHPSFVMMSLGNELWGSRERLGEIIDILRRENHSIFFTSGSNNFQFWPA
EIPQEDFFAGVRLSRDRLFRGSYAMCDAPLGHIQTDKPNTVHDYDAIIRGENGSENEGGD
TIQIQYGTGVKTVKLSAADGSYIPHKPVVSHEVGQYDYFPDFDEMKMYTGPLVPRYLDIF
RERLEERGLYTQWRDFFEAVGAHCTQCYKDEIETALRSSELSGFQLLDLQDFNGQGVSLV
GVLNAFMQSKGFITPEDWRGFCDSNVLLAKSEKYVFGADEKPAIEIILSSYGKDKINSGA
VRYSLRSDELDINGSVEFNSSDARLTSVGTFTPDFSAITKPQKAVLTLTFGKYHNGYVFW
LYPQTDVEITENCIKTADDELIFADSVEKAKELITSGKKAMVITDGSNAIENAYCADFWN
YHMFRVISESMNKPVAPGTMGLLIDKNDKLLSAFPSEKFTTPQWYEAVTHSKADILDDNP
EIIPIVQVVDNTERCHRLGMLYKKNGVLHCSIRLWEAADCPEIRQLAKSITENF

Enzyme Prediction     

No EC number prediction in MGYG000003844_00431.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	4	403	9.8e-53	0.46941489361702127

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	3.39e-19	5	586	13	583	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	9.66e-07	56	384	59	417	beta-D-glucuronidase; Provisional
pfam00703	Glyco_hydro_2	0.001	166	255	2	105	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam02836	Glyco_hydro_2_C	0.005	262	384	5	135	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBL34265.1	0.0	1	894	1	894
CBK95918.1	0.0	1	894	1	894
BAV13119.1	3.32e-257	1	890	1	909
ADL53165.1	3.32e-257	1	890	1	909
CCO04743.1	1.65e-254	1	892	1	901

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4JKM_A	3.71e-11	5	384	16	415	CrystalStructure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],4JKM_B Crystal Structure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],6CXS_A Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13],6CXS_B Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13]
6U7I_A	8.42e-11	149	384	183	412	Faecalibacteriumprausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_B Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_C Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_D Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii]
6U7J_A	1.10e-10	62	390	75	423	UnculturedClostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_B Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_C Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_D Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.]
1YQ2_A	3.91e-09	66	384	122	443	ChainA, beta-galactosidase [Arthrobacter sp. C2-2],1YQ2_B Chain B, beta-galactosidase [Arthrobacter sp. C2-2],1YQ2_C Chain C, beta-galactosidase [Arthrobacter sp. C2-2],1YQ2_D Chain D, beta-galactosidase [Arthrobacter sp. C2-2],1YQ2_E Chain E, beta-galactosidase [Arthrobacter sp. C2-2],1YQ2_F Chain F, beta-galactosidase [Arthrobacter sp. C2-2]
3GM8_A	7.20e-08	4	388	6	400	ChainA, Glycoside hydrolase family 2, candidate beta-glycosidase [Phocaeicola vulgatus ATCC 8482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
T2KPJ7	2.03e-13	6	386	55	432	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000056	0.000006	0.000002	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003844_00431.