CAZyme Information: MGYG000003875_00902

Basic Information

• Species: Firm-11 sp900540045
• Lineage: Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; Firm-11; Firm-11 sp900540045
• CAZyme ID: MGYG000003875_00902
• CAZy Family: GH127
• CAZyme Description: Non-reducing end beta-L-arabinofuranosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
634	MGYG000003875_7|CGC2	71782.11	4.94

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003875	3247365	MAG	United States	North America

• Gene Location: Start: 20370; End: 22274 Strand: -

Full Sequence      

MTGYRAHITGGFLKHYMDIIAHQALPYQWQVLSGMRDKNPTVRNFQIAAGEINGSFSGVP
YQDTDLAKWLDAVGCVLQNGPDRLLEQTADAIIETIVRAQDPDGYLDTYYQLVCPEKKWT
DPESHELYCFGHMIEAGVSYYEGTRKRSLLDVACRLADHVDRVFGPNEGQLHSYRGHEII
EMALMRLSAATGEARYSRLAEYLVAMRRDHPELFYRDGRREGNPLDYGCWGWGDPQRELS
SYEHVTGHAVRAMYLYCGMADVARETGDTVMAEHCDRLFHDVTDSQMYITGGIGTTAVLE
AYTYPYDLPNDTMYAETCASIGLCFFARRMLGLKNDRAYADTVERCVYNILPAAISQDGC
HYFYVNPLEVNEEACLKSPLKTHVKSRRQSWYECACCPPNLARMLASLPQYLYTVEDRRV
NIHLYAQSEAEIELNDGRLRISQMTDYPFGGRIVFSIGSQHPLDAAIALRIPQWCERYHL
TVDGEPVEEAPLVDGYRILERSWGTETEICLVLEISPEWIQANPRVREDAGKVAMAVGPV
VYCTEEADNGPLLSDLMVDTGTPLETMERNDVSGFGSYPAFSAAATRSSREAAGEKRLYF
PLVNRRRQVSMTLIPYCLWGERENGEMAVWLQGR

Enzyme Prediction     

No EC number prediction in MGYG000003875_00902.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	7	543	4.5e-192	0.9961832061068703

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3533	COG3533	5.35e-163	10	634	20	588	Uncharacterized conserved protein, DUF1680 family [Function unknown].
pfam07944	Glyco_hydro_127	4.72e-147	7	543	3	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADH61394.1	2.03e-195	8	632	19	646
AGB41651.1	3.45e-188	8	632	13	644
BCK00976.1	1.99e-183	5	631	14	650
BCJ94026.1	6.43e-183	7	632	17	656
ANF96932.1	2.19e-182	7	632	17	650

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4QJY_A	1.20e-176	12	631	22	645	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	1.59e-171	12	631	22	645	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
3WRE_A	5.59e-129	8	629	5	654	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	7.65e-129	8	629	5	654	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]
7EXU_A	2.14e-128	8	629	5	654	ChainA, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	3.06e-128	8	629	5	654	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000060	0.000004	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003875_00902.