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CAZyme Information: MGYG000003892_01566

You are here: Home > Sequence: MGYG000003892_01566

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Roseburia sp900753715
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia sp900753715
CAZyme ID MGYG000003892_01566
CAZy Family GH18
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
594 MGYG000003892_18|CGC1 66594.32 4.0921
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003892 2971162 MAG United States North America
Gene Location Start: 19734;  End: 21518  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003892_01566.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 217 581 1.4e-35 0.9290540540540541

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 4.56e-55 267 589 15 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 1.93e-38 267 589 116 418
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
smart00636 Glyco_18 3.69e-24 329 580 83 333
Glyco_18 domain.
pfam00704 Glyco_hydro_18 9.26e-22 337 579 88 305
Glycosyl hydrolases family 18.
cd06549 GH18_trifunctional 6.66e-20 268 586 14 298
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
VCV23980.1 3.93e-287 1 594 1 610
CBL13521.1 2.26e-286 1 594 1 610
CBL10290.1 2.26e-286 1 594 1 610
AEN98276.1 2.09e-267 2 594 5 589
ACR73835.1 1.63e-212 1 594 1 577

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4S3J_A 1.43e-13 317 591 172 423
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
3CZ8_A 1.54e-13 309 580 64 310
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4S3K_A 5.79e-12 273 586 130 420
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
5XWQ_A 2.35e-09 330 584 75 358
Crystalstructure of chitinase (RmChi1) from Rhizomucor miehei (sp p32 2 1, MR) [Rhizomucor miehei],5YUQ_A Chain A, Chintase [Rhizomucor miehei],5YUQ_B Chain B, Chintase [Rhizomucor miehei],7FBT_A Chain A, Chitinase [Rhizomucor miehei]
5XWF_A 1.29e-08 330 594 75 366
ChainA, Fungal chitinase from Rhizomucor miehei (SeMet-substituted proteins) [Rhizomucor miehei]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O31682 8.62e-18 275 476 22 221
Putative glycosylase YkvQ OS=Bacillus subtilis (strain 168) OX=224308 GN=ykvQ PE=3 SV=1
P37531 4.39e-13 292 594 144 424
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
O05495 1.30e-12 309 580 156 402
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P0DPJ9 1.81e-12 309 591 163 422
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
Q9K3E4 4.11e-11 317 591 171 422
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.668943 0.319068 0.003148 0.001068 0.000731 0.007045

TMHMM  Annotations      download full data without filtering help

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