CAZyme Information: MGYG000003902_01465

Basic Information

• Species: Veillonella dispar
• Lineage: Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Veillonellaceae; Veillonella; Veillonella dispar
• CAZyme ID: MGYG000003902_01465
• CAZy Family: GT51
• CAZyme Description: Monofunctional biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
268	MGYG000003902_13|CGC1	30735.99	6.6166

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003902	2119735	MAG	China	Asia

• Gene Location: Start: 18675; End: 19481 Strand: +

Full Sequence      

MKVFRYLRNLVVFVVVIILAVFIYDGYHSFQGTDRESKAHTTVEKRIEQSEDTLSRTDRI
IRIFTFKEKVESALNQRVSKEHWVKGDVIPEYTKNALIAIEDKRYYKHGAIDVLGIIRAF
YTNTIAGETVEGGSTITQQVVKNLFLSSKRIMSRKVEEAILASEMEHYYSKEEILTMYLN
TVYYGHNYYGIYEAAHGYFGTSPSRLTLGQSALLAALPNAPSYLDPYTNYKGAKARQKLV
LEQMVDQGMITQAEADYAYQQDLELVDE

Enzyme Prediction     

No EC number prediction in MGYG000003902_01465.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	78	245	3.6e-66	0.943502824858757

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00912	Transgly	4.34e-86	83	245	15	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG0744	MrcB	2.37e-82	57	263	52	259	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	5.56e-77	83	267	4	188	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009	MrcA	1.33e-65	84	263	70	249	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
PRK13481	PRK13481	5.85e-50	80	261	44	231	glycosyltransferase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
VEG94232.1	9.99e-178	1	268	1	268
CAB1277061.1	4.74e-176	1	268	1	268
SNV01217.1	1.30e-173	1	268	1	268
ACZ25247.1	1.30e-173	1	268	1	268
QQB17292.1	1.30e-173	1	268	1	268

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2OQO_A	3.66e-44	78	251	17	190	Crystalstructure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis [Aquifex aeolicus VF5],3D3H_A Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A [Aquifex aeolicus],3NB7_A Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with Decarboxylated Neryl Moenomycin [Aquifex aeolicus]
3NB6_A	1.45e-43	78	251	17	190	Crystalstructure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin [Aquifex aeolicus]
5ZZK_A	1.83e-36	79	261	55	243	ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50]
3HZS_A	1.93e-36	79	261	19	207	ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus MW2]
6FTB_A	1.98e-36	79	261	20	208	Staphylococcusaureus monofunctional glycosyltransferase in complex with moenomycin [Staphylococcus aureus MW2]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O87626	4.52e-41	80	263	67	250	Penicillin-binding protein 1A OS=Neisseria flavescens OX=484 GN=mrcA PE=3 SV=1
O86088	5.48e-40	86	263	74	250	Penicillin-binding protein 1A OS=Neisseria cinerea OX=483 GN=mrcA PE=3 SV=1
O87579	7.48e-40	86	263	74	250	Penicillin-binding protein 1A OS=Neisseria lactamica OX=486 GN=mrcA PE=3 SV=1
O05131	1.02e-39	86	263	74	250	Penicillin-binding protein 1A OS=Neisseria gonorrhoeae OX=485 GN=mrcA PE=1 SV=3
P0A0Z6	1.02e-39	86	263	74	250	Penicillin-binding protein 1A OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=mrcA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999621	0.000056	0.000166	0.000000	0.000000	0.000192

TMHMM  Annotations     

start	end
7	24