CAZyme Information: MGYG000003912_00636

Basic Information

• Species: Prevotella sp000435635
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp000435635
• CAZyme ID: MGYG000003912_00636
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
855	MGYG000003912_3|CGC4	97571.63	5.6195

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003912	2374877	MAG	China	Asia

• Gene Location: Start: 123651; End: 126218 Strand: -

Full Sequence      

MKRLSISFLFLFGLLCTYAAEPFIVFTKTESAFPVVSGGKPCSILVDDDEDKAILIAVQN
LQEDLLRVSGTKAETASTPTASQCILVGSVESPYIKQLFKDGKLNKKELQGKNEKYVIQT
VDQPMKGVDRALVIAGSDRRGTVYGIYELSKQMGVSPWYWWMDVPVVKRTDVYAKQGSYT
DGEPAVKYRGIFLNDEAPCLTSWVKNTYGTNYGDHNFYARVFELILRLKGNYLWPAMWGW
AFYADDPENGKTADEMGVCIGTSHHEPMARNHQEYARNRKAYGEWNYATNPEGLNRFFRE
GIERMKGTEDVVTIGMRGDGDAAMGGEEGKDHEYTPQFEKNMKLMESIFQNQRRIIKEVT
GRPAKETPQMWALYKEVLEYYERGLRVPDDVILLLCDDNWGNVRRLPNAKERKHPGGWGM
YYHVDYVGAPRNSKWLNVTPIQNMWEQLQLTYDYGVDKLWILNVGDLKPMEYPITLFMDM
AWNPKKYQAGNLLSHTRDFCAAAFGEEQADEATRILNLCCKYNGRSTAEMLDRTVYNLET
GEWRQVVGDYAQLEAEALRQYISLKPEYRDAYKQLILFPVQAMANLHEMYYAQAMNLKLY
AEGNPAANEWADKVEKAFARDKQLCDDYNHTMANGKWNGMMTQKHIGYTQWNDNFPADKL
PEIRRVESPETAVGGYVFTGKDGYVAMEAEHYFSSVNAPEAQWTVLPYMGRTLSGMALMP
YTVQTDGASLSYKMTIPEKVDSVTIHVIVKSTLAFHNQEGHKYTIGFEDGQEETINFNGN
LNEDPENIYSVYYPTVARRVVEKKVSVKLPASADNTYTLNFRPLDPGIVLEKIVVDYGGY
QPSYLFGNESPCKRK

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	31	833	7.1e-281	0.9971305595408895

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	182	530	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.05e-42	677	845	1	168	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	5.91e-06	54	149	33	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).
pfam05124	S_layer_C	0.001	43	151	109	219	S-layer like family, C-terminal region.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT26893.1	0.0	1	854	1	842
QDH54071.1	0.0	1	854	1	842
QUR44901.1	0.0	1	854	1	842
ALJ48348.1	0.0	1	855	1	843
EDO10816.1	0.0	1	855	12	854

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	1	855	12	854	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	0.0	33	854	17	838	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	0.0	33	854	16	837	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	5.17e-172	43	682	24	650	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	2.39e-126	85	654	65	648	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000424	0.998666	0.000394	0.000170	0.000153	0.000147

TMHMM  Annotations     

start	end
5	27