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CAZyme Information: MGYG000003945_00023

You are here: Home > Sequence: MGYG000003945_00023

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-138; ;
CAZyme ID MGYG000003945_00023
CAZy Family GT39
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1316 MGYG000003945_1|CGC1 144800.97 6.6256
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003945 1915939 MAG United Kingdom Europe
Gene Location Start: 24487;  End: 28437  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003945_00023.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 872 1114 4.6e-56 0.9237668161434978

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16192 PMT_4TMC 6.77e-24 1134 1288 3 172
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG5542 COG5542 8.19e-20 264 635 43 398
Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].
COG1928 PMT1 9.93e-17 872 1297 44 680
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam02366 PMT 1.34e-10 871 1043 16 197
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
pfam13231 PMT_2 2.29e-09 900 1046 1 138
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ASA25569.1 7.83e-238 2 1296 3 1251
QGQ95357.1 1.78e-235 28 1293 35 1259
QWU18200.1 2.11e-235 1 1296 2 1256
QSF45552.1 1.16e-234 1 1296 1 1256
BCG57259.1 1.68e-234 1 1296 1 1257

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WN04 9.69e-32 878 1296 73 507
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 9.69e-32 878 1296 73 507
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
L8F4Z2 2.42e-27 878 1296 67 501
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
Q8NRZ6 6.49e-17 901 1297 99 506
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000261 0.998943 0.000216 0.000195 0.000186 0.000160

TMHMM  Annotations      download full data without filtering help

start end
225 247
260 282
319 341
374 396
425 447
460 482
532 554
574 593
597 611
618 640
655 677
726 748
920 942
976 998
1024 1046
1088 1110
1190 1212
1219 1236
1240 1259
1272 1294