CAZyme Information: MGYG000003987_01784

Basic Information

• Species: UBA1691 sp900544375
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UBA1691; UBA1691 sp900544375
• CAZyme ID: MGYG000003987_01784
• CAZy Family: GH110
• CAZyme Description: Alpha-1,3-galactosidase A

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
832		92052.24	6.7328

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003987	2710592	MAG	United Kingdom	Europe

• Gene Location: Start: 4395; End: 6893 Strand: +

Full Sequence      

METNRTILRVTDYGADPAGKGDSAKALQAALEAARNTPGPVTLFFPRGEYHFYKEHAQRR
VYHTSNTDSCSHPEKAIAILIEDQEDLMLDGGGSLFLMHGNMMALAVVRSKQITLRAFAW
DFAVPTVSEMTVAGFGQKGISQYTDFYIPAAFPFRLSGRRKLLWTGGAGMDGAPYWTEKN
HHAGWSVVGYDPSAGVSRRYSLLQGPFSHVWKLEQLAPNRVRVFYFGKRPGVQKLGMVYE
LCASKTRETAGAFHWESEDLLIEQVNVHYMHGFGWLTQMCRNVTYRDCRFMPRPGTGKFT
TSFADLIHASGVGGRMTIENCVFGHAHDDPINLHGTFTRVERRLDARTLTLRYIHKQQGG
FPQFHTGDEVIFYARDTLAPLCGKEERYRVVKSIDPGAGGNDLKTMTVTFDRDLPKEITA
QIGPQPKYVAENVTYTAEVVIRNNFFTTIPTRGILCTQRRKVLIENNVFQNMAMASIFLS
NDSNEWYESGPIRDLTIRGNTFYVRPAGQTEWKYKPAVYIHPEVKGGSSKLSADTPVHRN
ITIEENTFYMGHDSVVRAEGVAGLIFRRNRVLRDAPGIHLHISPETCALKAGEWVSLQTQ
AEGRRNQAEEDLLFSFEACSQVTLADNTYDNGLKMGAALIRTRREAIECEDALTFDAQCP
ASAPVGAITYHSTEESVVTVDKGTLTAKAPGAAYVYAQTLWNGVAIQSNWIPVCVGEAEL
PPEREPESAVCDARVTIPALLFDTAGASEQSIAITTAPDCGLERIEIQLSADETAGEIAL
CTGDERVIIAQAQGRELSVGVPLAPGLNSFYARVTAHNGQVSSERAVHIIKI

Enzyme Prediction     

No EC number prediction in MGYG000003987_01784.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH110	8	591	1.5e-147	0.9799270072992701

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam12708	Pectate_lyase_3	7.89e-07	10	50	4	44	Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.
pfam13229	Beta_helix	1.29e-05	432	583	4	123	Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
PLN02218	PLN02218	8.59e-04	6	94	66	165	polygalacturonase ADPG
pfam13229	Beta_helix	0.003	432	503	73	135	Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
PLN02188	PLN02188	0.007	4	50	33	79	polygalacturonase/glycoside hydrolase family protein

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AYE35188.1	4.42e-247	3	725	41	768
QAS60591.1	6.24e-247	3	725	41	768
ATD55583.1	6.35e-217	8	634	3	595
ATD56740.1	6.35e-217	8	634	3	595
QBJ75880.1	6.80e-217	8	634	5	597

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7JW4_A	7.17e-44	1	569	21	564	Crystalstructure of PdGH110B in complex with D-galactose [Pseudoalteromonas distincta],7JW4_B Crystal structure of PdGH110B in complex with D-galactose [Pseudoalteromonas distincta]
7JWF_A	3.20e-43	1	569	21	564	Crystalstructure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_B Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_C Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_D Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
B1V8K7	1.25e-132	3	715	30	723	Alpha-1,3-galactosidase A OS=Streptacidiphilus griseoplanus OX=66896 GN=glaA PE=1 SV=1
Q826C5	2.35e-117	7	633	40	618	Alpha-1,3-galactosidase A OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) OX=227882 GN=glaA PE=3 SV=1
Q64MU6	3.20e-80	5	573	23	552	Alpha-1,3-galactosidase A OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=glaA PE=3 SV=1
Q5L7M8	2.30e-79	5	573	23	552	Alpha-1,3-galactosidase A OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=glaA PE=3 SV=1
Q8A2Z5	6.75e-77	20	571	24	532	Alpha-1,3-galactosidase A OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=glaA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000046	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003987_01784.