CAZyme Information: MGYG000003994_01553

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; UBA11471; UBA11471
• CAZyme ID: MGYG000003994_01553
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1003		112718.47	6.4498

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003994	2451435	MAG	United Kingdom	Europe

• Gene Location: Start: 6992; End: 10003 Strand: +

Full Sequence      

MHNDLKKIFLLFLLCGTAWLATAQARQTPRLMREVDQRAMNQWVDSVMQRLSVPERIGQL
FVVGVENNLNERNKERLRALIEQCHVGGLLFSKGTAPDQATLTNMAQSLARVPLLITMDG
EWGLAMRLKDTPSYPRNMTLGAVADDSLIYAYGREMGRACRRMGIQVNFAPVLDVNSNPQ
NPVIGNRSFGENPDNVSRKARLYAQGLEDEGVMAVGKHFPGHGDTHEDSHHTLPSVLRDR
AHLDTCELLPFTRYIRAGFSGLMVGHLLVPALDSTGSRPSSLSPRIVTSLLQEEMGFDGL
IFTDALEMKGARSASIALDALLAGNDILLKPLKPEAEFEQLLQSYQNGTLPQEIIDRHCR
KVLQYKYILGLHTRPTVETDSLTEELNSPESRLLIRRLSAQAITLLENRDEVLPFTHLNR
QRFGVITVGAQNAAPFVNRLREYAPISYVSRLHAASSEEEIKGIIDVITHSTTTIVALFS
RKEEDRQLAQKILKKAKGKILVFFTSPYTLPEYDALIAEADAVVMAYENTPVMQECAAEA
LFGGSATDGKLPVTAGPYPAGSGLYTPECRLGHAYPEEVGMDSRTLCHIDSIVQEGIDSM
AFPGCQIVITRHKKIIYDRAFGHFDYEKSHAVESDDLYDLASITKAMGTLPAIMWLNDHE
QVSLNAPLCFYLPEMRDYGLSAITLRQTLMHESGLPAGISLRRLLIDPDSYTPPLLKRGR
DSEYPVQVDREWFARQESRLKPWLFNEEKNKTFPTLIADGLYASPSLSDSIWHKILSVSR
ADRQYRYSDLNFVILQKLTERVSGEPLDRFIDRRLLQPIGAYHTTFKPREKFPVSQIAPT
ENDQLFRKQLITGYPHDELACFLGGVSGNAGLFSNARDMVKILQMLQNNGTYGLEDYFEP
TTVLKFTTEKSSLSRRGLGFDKPDPERPQNSPTCEEAPASVYGHTGYTGTAFWVDPDNDI
IYIFLSNRVYPHRWNTRLFDTNIRTRIQSVIYQSLQPDSLSVE

Enzyme Prediction     

No EC number prediction in MGYG000003994_01553.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	107	329	4.6e-57	0.9768518518518519

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	1.55e-77	51	432	1	366	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	7.36e-70	52	363	1	314	Glycosyl hydrolase family 3 N terminal domain.
PRK03642	PRK03642	7.47e-48	571	996	25	432	putative periplasmic esterase; Provisional
PRK05337	PRK05337	3.18e-46	62	329	8	278	beta-hexosaminidase; Provisional
pfam00144	Beta-lactamase	1.02e-45	589	973	1	313	Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCI64113.1	0.0	8	996	6	994
AHF12964.1	0.0	5	995	1	987
QIK59886.1	0.0	23	996	22	992
QIK54477.1	0.0	23	995	22	991
BBK92319.1	4.42e-300	5	999	1	995

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6K5J_A	1.95e-62	51	552	11	528	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3BMX_A	2.72e-58	33	564	22	634	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
4GYJ_A	1.39e-57	33	564	26	638	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
3LK6_A	1.46e-57	45	564	10	608	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
3SQL_A	3.40e-51	71	539	44	533	CrystalStructure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQL_B Crystal Structure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQM_A Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_B Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_C Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_D Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	1.49e-57	33	564	22	634	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	6.07e-46	77	444	55	453	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
Q7WUL3	1.19e-41	43	555	18	555	Beta-N-acetylglucosaminidase/beta-glucosidase OS=Cellulomonas fimi OX=1708 GN=nag3 PE=1 SV=1
L7N6B0	7.41e-39	51	366	59	380	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
A0A0H3M1P5	1.00e-38	51	366	59	380	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000227	0.999189	0.000160	0.000141	0.000131	0.000126

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003994_01553.