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CAZyme Information: MGYG000003999_01481

You are here: Home > Sequence: MGYG000003999_01481

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; CAG-521;
CAZyme ID MGYG000003999_01481
CAZy Family GT2
CAZyme Description Cellulose synthase catalytic subunit [UDP-forming]
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
860 MGYG000003999_32|CGC1 97197.65 8.6559
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003999 1640178 MAG United Kingdom Europe
Gene Location Start: 1152;  End: 3734  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.12

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT2 274 445 1.3e-38 0.9941176470588236

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK11498 bcsA 0.0 15 858 9 850
cellulose synthase catalytic subunit; Provisional
TIGR03030 CelA 0.0 142 822 5 702
cellulose synthase catalytic subunit (UDP-forming). Cellulose synthase catalyzes the beta-1,4 polymerization of glucose residues in the formation of cellulose. In bacteria, the substrate is UDP-glucose. The synthase consists of two subunits (or domains in the frequent cases where it is encoded as a single polypeptide), the catalytic domain modelled here and the regulatory domain (pfam03170). The regulatory domain binds the allosteric activator cyclic di-GMP. The protein is membrane-associated and probably assembles into multimers such that the individual cellulose strands can self-assemble into multi-strand fibrils.
cd06421 CESA_CelA_like 2.33e-119 271 503 1 234
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.
COG1215 BcsA 1.09e-56 222 683 4 430
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd06437 CESA_CaSu_A2 3.80e-37 271 498 1 231
Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QQS88758.1 0.0 17 852 20 861
QDA53875.1 0.0 9 853 12 875
QQQ96025.1 6.91e-316 10 851 14 873
ANU67170.1 6.91e-316 10 851 14 873
QDA53780.1 1.70e-276 128 851 40 766

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7LBY_A 1.27e-265 10 854 17 859
ChainA, Cellulose synthase catalytic subunit [UDP-forming] [Escherichia coli K-12]
5EJ1_A 1.03e-109 144 703 3 577
ChainA, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]
4HG6_A 6.30e-109 144 703 15 589
ChainA, Cellulose Synthase Subunit A [Cereibacter sphaeroides]
4P00_A 6.45e-109 144 703 16 590
ChainA, Cellulose Synthase A subunit [Cereibacter sphaeroides 2.4.1],4P02_A Chain A, Cellulose Synthase subunit A [Cereibacter sphaeroides 2.4.1],5EIY_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1],5EJZ_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P37653 3.82e-266 10 854 17 859
Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli (strain K12) OX=83333 GN=bcsA PE=1 SV=3
Q8X5L7 7.65e-266 10 854 17 859
Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli O157:H7 OX=83334 GN=bcsA PE=3 SV=2
Q8Z291 6.27e-260 17 853 24 858
Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhi OX=90370 GN=bcsA PE=3 SV=1
Q93IN2 1.26e-259 17 853 24 858
Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=bcsA PE=3 SV=1
P58931 6.10e-208 156 797 44 683
Cellulose synthase catalytic subunit [UDP-forming] OS=Pseudomonas fluorescens (strain SBW25) OX=216595 GN=bcsA PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.969385 0.029176 0.000279 0.000089 0.000068 0.001017

TMHMM  Annotations      download full data without filtering help

start end
21 43
75 97
147 166
171 188
195 214
234 256
520 539
543 565
586 608
636 653
666 688