logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000004003_00869

You are here: Home > Sequence: MGYG000004003_00869

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides;
CAZyme ID MGYG000004003_00869
CAZy Family PL13
CAZyme Description Heparin lyase I
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
392 MGYG000004003_10|CGC3 44183.29 9.1179
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004003 5653807 MAG United Kingdom Europe
Gene Location Start: 53767;  End: 54945  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.7

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL13 23 392 3.5e-205 0.9944903581267218

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam14099 Polysacc_lyase 2.03e-18 52 379 9 200
Polysaccharide lyase. This family includes heparin lyase I, EC:4.2.2.7. Heparin lyase I depolymerizes heparin by cleaving the glycosidic linkage next to an iduronic acid moiety. The structure of heparin lyase I consists of a beta-jelly roll domain with a long, deep substrate-binding groove and an unusual thumb domain containing many basic residues extending from the main body of the enzyme. This family also includes glucuronan lyase, EC:4.2.2.14. The structure glucuronan lyase is a beta-jelly roll.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIU95134.1 3.71e-281 1 392 1 392
QRQ56254.1 7.36e-272 1 392 1 392
SCV08896.1 7.36e-272 1 392 1 392
ALJ49472.1 7.36e-272 1 392 1 392
QNL36937.1 2.11e-271 1 392 1 392

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3IKW_A 1.70e-251 19 392 1 374
Structureof Heparinase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron]
3IMN_A 2.31e-250 18 392 2 376
Crystalstructure of heparin lyase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron],3IN9_A Crystal structure of heparin lyase I complexed with disaccharide heparin [Bacteroides thetaiotaomicron]
3ILR_A 5.71e-249 23 392 1 370
Structureof Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product [Bacteroides thetaiotaomicron]
3INA_A 7.70e-249 18 392 2 376
Crystalstructure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin [Bacteroides thetaiotaomicron]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q05819 8.67e-170 1 391 1 381
Heparin lyase I OS=Pedobacter heparinus OX=984 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000857 0.573817 0.424534 0.000363 0.000219 0.000190

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004003_00869.