CAZyme Information: MGYG000004019_00398

Basic Information

• Species: Bacteroides massiliensis_A
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides massiliensis_A
• CAZyme ID: MGYG000004019_00398
• CAZy Family: CBM67
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
744	MGYG000004019_3|CGC1	85186.98	6.8544

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004019	3250001	MAG	United Kingdom	Europe

• Gene Location: Start: 53243; End: 55477 Strand: -

Full Sequence      

MKRGRGVSKYIYSFTFFSFLCIWMTYAQVLTLPASEAVSPGMWLCYRMNVPLNDEPSEVE
LRIAADSKYWLWVNGELQVREGGLKRGPNPKDTYCDVLQGRHGLRKGDNLVAVLVWYFGK
DGFSHRNSPTPGLAFRLSVNGEALDTDSAWKVRRHPAYYLPEGEEPNYRLPESNIGFDAR
KDIPFQQADYDDSGWGRARLVSLEEAGWNGLAVRPIPQWKDYGLKTYARTERQGNRILAY
LPYNAQVTPYIKLKAAAGHRIDIRTDDYRGGSATNVFAEYTTCEGVQEFECHGWMNGHYV
IYTIPEGCEVLELKYRETGYDTDFAGSFWCDDPFLTRLWTKSQRTLYITMRDTYMDCPDR
ERAQWWGDVVNELGEAFYALDEKAHRLTRKGICELMDWQRADSTIFAPVPAGNYKDELPM
QMLASVGYYGFWAYYMGTGDKELIEYVFPKVKKYIHVWKTSSDGLVIPRQGGWTWGDWGD
NKDMELLFNLWYSIALDGYARMARLVGEVEEASWADKVNLRLRQVFHQKYWTGSYYKSPD
YKGLPDDRAQALAIVAGVLPKELYPVIRPFFKEQYHASPYMEKYVLQALCEMGYYQDAMD
RMKLRYGAMVDSPLTTLWEGWGIGNEGFGGGSYNHAWSGGPLTILSSYIAGIQVVEPGFK
AFSVCPNLGNLNQVKVSVPLSGGRPIRTDLKKTPVGCTLELVVPEETTAILELPDGYTRM
KVNGKLKKQEVRLKEGRWQICFIR

Enzyme Prediction     

No EC number prediction in MGYG000004019_00398.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH78	256	713	8.9e-85	0.9444444444444444
CBM67	37	202	3.3e-27	0.8977272727272727

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam17389	Bac_rhamnosid6H	3.57e-34	323	649	1	340	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.
pfam17390	Bac_rhamnosid_C	8.24e-08	651	716	1	66	Bacterial alpha-L-rhamnosidase C-terminal domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.
pfam08531	Bac_rhamnosid_N	1.17e-05	104	206	52	158	Alpha-L-rhamnosidase N-terminal domain. This family consists of bacterial rhamnosidase A and B enzymes. This domain is probably involved in substrate recognition.
pfam04685	DUF608	6.13e-05	432	537	109	217	Glycosyl-hydrolase family 116, catalytic region. This represents a family of archaeal, bacterial and eukaryotic glycosyl hydrolases, that belong to superfamily GH116. The primary catabolic pathway for glucosylceramide is catalysis by the lysosomal enzyme glucocerebrosidase. In higher eukaryotes, glucosylceramide is the precursor of glycosphingolipids, a complex group of ubiquitous membrane lipids. Mutations in the human protein cause motor-neurone defects in hereditary spastic paraplegia. The catalytic nucleophile, identified in UniProtKB:Q97YG8_SULSO, is a glutamine-335, with the likely acid/base at Asp-442 and the aspartates at Asp-406 and Asp-458 residues also playing a role in the catalysis of glucosides and xylosides that are beta-bound to hydrophobic groups. The family is defined as GH116, which presently includes enzymes with beta-glucosidase, EC:3.2.1.21, beta-xylosidase, EC:3.2.1.37, and glucocerebrosidase EC:3.2.1.45 activity.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNL36670.1	0.0	14	742	9	738
QDH54696.1	0.0	27	742	22	738
QLG44645.1	1.08e-267	33	725	31	729
AGY53286.1	5.98e-258	27	726	28	735
QUT48047.1	1.54e-254	43	734	40	735

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4XHC_A	4.95e-06	332	648	213	541	ChainA, Alpha-L-rhamnosidase [Klebsiella oxytoca],4XHC_B Chain B, Alpha-L-rhamnosidase [Klebsiella oxytoca]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.564153	0.417876	0.012401	0.001005	0.000598	0.003955

TMHMM  Annotations     

start	end
12	34