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CAZyme Information: MGYG000004043_00288
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; UBA7173; | |||||||||||
| CAZyme ID | MGYG000004043_00288 | |||||||||||
| CAZy Family | GH127 | |||||||||||
| CAZyme Description | Beta-galactosidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 59309; End: 63448 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH127 | 36 | 546 | 1.5e-198 | 0.9980916030534351 |
| GH2 | 614 | 1275 | 1.5e-120 | 0.7579787234042553 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG3533 | COG3533 | 4.86e-179 | 33 | 614 | 9 | 589 | Uncharacterized conserved protein, DUF1680 family [Function unknown]. |
| pfam07944 | Glyco_hydro_127 | 4.06e-174 | 35 | 546 | 1 | 503 | Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context. |
| COG3250 | LacZ | 2.67e-68 | 618 | 1144 | 7 | 533 | Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]. |
| pfam18565 | Glyco_hydro2_C5 | 4.66e-47 | 1273 | 1374 | 1 | 102 | Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme. |
| PRK10150 | PRK10150 | 1.80e-42 | 630 | 1052 | 19 | 447 | beta-D-glucuronidase; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ASB48009.1 | 9.41e-252 | 626 | 1376 | 25 | 806 |
| SCM56443.1 | 2.41e-244 | 7 | 612 | 13 | 623 |
| BBD46518.1 | 8.69e-241 | 26 | 614 | 34 | 624 |
| QIX65272.1 | 1.10e-239 | 25 | 614 | 29 | 618 |
| BBK93301.1 | 2.19e-239 | 25 | 614 | 29 | 618 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4YPJ_A | 2.80e-157 | 623 | 1369 | 7 | 798 | ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans] |
| 7CWD_A | 4.53e-157 | 624 | 1376 | 2 | 799 | ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans] |
| 4QJY_A | 1.55e-150 | 34 | 611 | 14 | 646 | Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus] |
| 6EX6_A | 6.81e-146 | 30 | 630 | 9 | 645 | TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482] |
| 5T98_A | 7.70e-146 | 626 | 1379 | 30 | 821 | Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A7LXS9 | 5.05e-164 | 626 | 1379 | 47 | 849 | Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1 |
| E8MGH8 | 5.81e-114 | 56 | 609 | 41 | 655 | Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1 |
| T2KM09 | 3.60e-90 | 621 | 1366 | 46 | 808 | Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2 |
| P77989 | 1.36e-73 | 625 | 1366 | 5 | 725 | Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2 |
| T2KPJ7 | 1.02e-58 | 620 | 1346 | 50 | 799 | Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000780 | 0.728721 | 0.269633 | 0.000313 | 0.000291 | 0.000253 |