CAZyme Information: MGYG000004056_00311

Basic Information

• Species: Alistipes_A ihumii
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes_A; Alistipes_A ihumii
• CAZyme ID: MGYG000004056_00311
• CAZy Family: GH127
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
629	MGYG000004056_11|CGC1	70358.71	5.1853

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004056	2329828	MAG	United Kingdom	Europe

• Gene Location: Start: 18760; End: 20649 Strand: +

Full Sequence      

MKKQLLTAAILCCLAVAGSTAAPKSAKKKPKIPVSRVQTHMEGYLGDRIDACIRVRVCSE
DPELLVAPMRRQTETSLWQSEFWGKWTLGAIASYRYNKDPELLRKIEGGVESLLAAQQPD
GYIGNYAPEAQLTNWDVWGRKYTMLGLLAYYDLTGDKKALEGAVRLADHLLTQIPAVRQI
ERTGIYRGMSSCSILEPIMLLYNRTLDERYLDFARYIVDRMESADGPQLIAKALDGVPVS
ERFPLADPQGWFVWENGQKAYEMMSCYDGLLELYKVTNEPRYLEAVEATVANIIADEINI
AGSGSSFECFYKGKALQTEPAYHTMETCVTMTWMKLCYDLLRLTRNPLYADQIERSAYNA
LVASMKEDASQIAKYSPLEGARSAGEEQCGMHVNCCNMNGPRAFALLPEVAVTDHGDELF
VNLYGPMSSAVGLDGGEVLLEQATSYPEQGDIEIRIDPRKSFEFTVSLRIPAWSAVSMVT
VNGQSVDGVTPGEYLRLKRRWEPGDRIGVKLDMRGRLIRQGGFQAIERGPVVLARDTRFG
DGFVDEAVVVQATDGFVTLLPVEEKPEKMWMAFTAPMILGTDLEGELAAPRQIMLCDFAS
AGNTWNRNIRYRVWLRRTLNLMKPDGNSR

Enzyme Prediction     

No EC number prediction in MGYG000004056_00311.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	71	533	5.7e-59	0.9122137404580153

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	3.06e-65	84	534	61	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	8.17e-62	43	534	21	501	Uncharacterized conserved protein, DUF1680 family [Function unknown].
PTZ00470	PTZ00470	4.56e-07	146	328	163	351	glycoside hydrolase family 47 protein; Provisional
COG4225	YesR	4.72e-05	135	284	34	158	Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism].
cd04791	LanC_SerThrkinase	3.46e-04	88	215	93	228	Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ARE60508.1	2.37e-205	41	622	29	613
QHS51661.1	7.90e-48	85	536	123	582
AZO44522.1	6.83e-42	20	532	2	560
AXC10260.1	1.39e-41	25	535	83	592
AIQ52276.1	4.98e-40	66	556	59	604

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6EX6_A	1.85e-35	89	539	78	553	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
4QJY_A	1.22e-32	85	532	81	558	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	2.32e-30	85	532	81	558	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
5MQO_A	4.42e-24	79	513	90	579	Glycosidehydrolase BT_1003 [Bacteroides thetaiotaomicron]
3WRE_A	1.80e-19	85	552	80	596	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	9.85e-19	85	552	80	596	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000341	0.998869	0.000280	0.000172	0.000161	0.000156

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004056_00311.