CAZyme Information: MGYG000004094_01632

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae
• CAZyme ID: MGYG000004094_01632
• CAZy Family: GH23
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
324	MGYG000004094_10|CGC3	36831.36	9.9507

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004094	3605841	MAG	United Kingdom	Europe

• Gene Location: Start: 99299; End: 100273 Strand: -

Full Sequence      

MKKSIRSVIFISSIAVASASIPFLIGSAPAEVEKVMKQEGSYSVTPPDVPKQVTFAGEAI
DLTPYDRRERMDRELSSFTYMHSTTMLMIKRANRYFPIVEPILKANGIPDDFKYLMVIES
NLSTLARSPVGAAGLWQFMDTTGRSHGLEVNKNVDERYNIRKATKAACKYLKEGYAQYGD
WITVAASYNAGKGRISTELNKQEVDSALDLWLNQETSRYMFRILAAKEVFNNPKRFGFLL
KKESLYPPIPFKEVKVNTRIADLAQFAKQNGITYAQLKDANPWLRDRFLENRSGKTYTLL
IPTKEGMNYDPSKTVPYNKNWVIN

Enzyme Prediction     

No EC number prediction in MGYG000004094_01632.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH23	95	229	1.1e-21	0.8962962962962963

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd16894	MltD-like	4.64e-59	103	228	1	129	Membrane-bound lytic murein transglycosylase D and similar proteins. Lytic transglycosylases (LT) catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc). Membrane-bound lytic murein transglycosylase D protein (MltD) family members may have one or more small LysM domains, which may contribute to peptidoglycan binding. Unlike the similar "goose-type" lysozymes, LTs also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).
PRK10783	mltD	5.44e-26	68	282	81	293	membrane-bound lytic murein transglycosylase D; Provisional
pfam01464	SLT	3.56e-21	98	195	1	99	Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.
cd00254	LT-like	2.46e-14	115	226	7	109	lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd13401	Slt70-like	6.28e-14	95	231	6	150	70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QRP57342.1	5.39e-162	1	323	1	325
QGT73861.1	5.39e-162	19	323	21	325
QQT77414.1	5.39e-162	1	323	1	325
ASM66026.1	5.39e-162	1	323	1	325
ALJ49292.1	6.63e-162	19	323	17	321

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P0AEZ7	1.16e-23	68	304	78	310	Membrane-bound lytic murein transglycosylase D OS=Escherichia coli (strain K12) OX=83333 GN=mltD PE=1 SV=1
P0AEZ8	1.16e-23	68	304	78	310	Membrane-bound lytic murein transglycosylase D OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=mltD PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.076223	0.917360	0.004571	0.001175	0.000347	0.000298

TMHMM  Annotations     

start	end
7	29