logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000004107_00996

You are here: Home > Sequence: MGYG000004107_00996

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; Firm-11;
CAZyme ID MGYG000004107_00996
CAZy Family GT39
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1399 155395.66 6.5357
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004107 2102916 MAG United Kingdom Europe
Gene Location Start: 2339;  End: 6538  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004107_00996.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 910 1143 2.2e-53 0.9147982062780269

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16192 PMT_4TMC 3.96e-21 1153 1317 1 170
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG1928 PMT1 1.91e-20 914 1148 50 277
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam02366 PMT 1.21e-15 907 1114 16 225
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG4346 COG4346 1.17e-14 930 1227 129 360
Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].
COG1928 PMT1 1.39e-13 1152 1295 498 637
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUC68008.1 2.61e-309 2 1399 5 1422
QTE75201.1 1.11e-304 1 1399 3 1422
QTE71236.1 1.98e-304 16 1399 6 1407
QUA53848.1 7.95e-303 5 1389 17 1362
QTE68569.1 2.15e-302 2 1389 8 1392

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6P25_A 1.93e-06 908 1090 70 253
Structureof S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WN04 1.19e-23 914 1293 73 461
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 1.19e-23 914 1293 73 461
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
L8F4Z2 7.85e-20 903 1293 56 455
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000205 0.999175 0.000164 0.000166 0.000146 0.000136

TMHMM  Annotations      download full data without filtering help

start end
5 22
215 234
243 262
305 327
355 377
409 431
444 466
486 505
512 530
540 557
564 583
587 606
613 632
636 658
671 693
732 754
956 978
1007 1026
1047 1066
1070 1087
1117 1139
1213 1235
1254 1271
1276 1298
1305 1327
1361 1383