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CAZyme Information: MGYG000004113_01654

You are here: Home > Sequence: MGYG000004113_01654

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-272 sp000433515
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; CAG-272; CAG-272 sp000433515
CAZyme ID MGYG000004113_01654
CAZy Family GH36
CAZyme Description Alpha-galactosidase Mel36A
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
723 80860.13 4.7622
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004113 2413053 MAG United Kingdom Europe
Gene Location Start: 51491;  End: 53662  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004113_01654.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH36 119 708 1.6e-45 0.8343023255813954

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14791 GH36 1.14e-12 349 568 29 238
glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam02065 Melibiase 2.61e-10 377 573 93 284
Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
pfam16874 Glyco_hydro_36C 4.55e-07 643 710 1 65
Glycosyl hydrolase family 36 C-terminal domain. This domain is found at the C-terminus of many family 36 glycoside hydrolases. It has a beta-sandwich structure with a Greek key motif.
COG3345 GalA 0.001 349 711 319 669
Alpha-galactosidase [Carbohydrate transport and metabolism].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BBO33728.1 4.91e-113 55 719 19 681
QOY88337.1 3.26e-103 82 722 171 788
BBO33698.1 2.26e-101 67 717 32 680
QGA23733.1 2.41e-100 63 723 31 673
QGQ94285.1 8.78e-99 65 722 4 644

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6JHP_A 5.52e-06 349 548 386 581
Crystalstructure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila [Paecilomyces sp. 'thermophila'],6JHP_B Crystal structure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila [Paecilomyces sp. 'thermophila'],6JHP_C Crystal structure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila [Paecilomyces sp. 'thermophila'],6JHP_D Crystal structure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila [Paecilomyces sp. 'thermophila']
6PHU_A 7.20e-06 351 709 372 723
SpAgawild type apo structure [Streptococcus pneumoniae TIGR4],6PHV_A Chain A, Alpha-galactosidase [Streptococcus pneumoniae TIGR4]

Swiss-Prot Hits      help

has no Swissprot hit.

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000000 0.000000 1.000037 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004113_01654.