CAZyme Information: MGYG000004126_02186

Basic Information

• Species: Fournierella sp900543285
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Fournierella; Fournierella sp900543285
• CAZyme ID: MGYG000004126_02186
• CAZy Family: CE7
• CAZyme Description: Cephalosporin-C deacetylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
327	MGYG000004126_34|CGC1	36636.72	5.396

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004126	3496226	MAG	United Kingdom	Europe

• Gene Location: Start: 26110; End: 27093 Strand: -

Full Sequence      

MPQIDWPLEQLKTYRGKSPKPADWQAYWDRALKELEAADPACTYEKDPVTVPGVECGHLW
FTGVGGARVHAQLMRPTGFAGPRPAVLLFHGYEGHSHDWYEKLPFAQSGIAVAALDVRGQ
AGFSQDTLQITGSTFRGHIVRGVDEEDPDKLFFRNVYLDTVQLARIVAGLEFVDESRLAS
VGFSQGGALAIACAALSGQMGRTVAGYPFLADFCRVRELDYPNPAYDELKLYFRLRDPRH
EKENGFFERLGYLDAQWMAEKLTAPVLFYTGLADMICPPSCQFAVYNRITAPKRQVIYPD
YGHELLPGAWQEILLWLLEWAAGGQTL

Enzyme Prediction     

No EC number prediction in MGYG000004126_02186.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CE7	4	316	1.2e-97	0.987220447284345

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam05448	AXE1	6.18e-117	4	317	3	314	Acetyl xylan esterase (AXE1). This family consists of several bacterial acetyl xylan esterase proteins. Acetyl xylan esterases are enzymes that hydrolyze the ester linkages of the acetyl groups in position 2 and/or 3 of the xylose moieties of natural acetylated xylan from hardwood. These enzymes are one of the accessory enzymes which are part of the xylanolytic system, together with xylanases, beta-xylosidases, alpha-arabinofuranosidases and methylglucuronidases; these are all required for the complete hydrolysis of xylan.
COG3458	Axe1	8.79e-102	1	317	1	314	Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, transport and catabolism].
COG1506	DAP2	3.50e-17	58	322	367	614	Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism].
pfam12146	Hydrolase_4	1.54e-12	82	306	3	233	Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
COG0412	DLH	1.60e-07	66	210	11	146	Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QKS47765.1	5.47e-118	1	319	1	318
AIQ46134.1	1.10e-117	1	318	1	317
AVM46423.1	3.36e-117	4	308	3	307
AIQ51745.1	4.45e-117	1	318	1	317
ASS68552.1	8.95e-117	1	319	1	318

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3FCY_A	1.47e-100	4	319	30	343	CrystalStructure of Acetyl Xylan Esterase 1 from Thermoanaerobacterium sp. JW/SL YS485 [Thermoanaerobacterium saccharolyticum JW/SL-YS485],3FCY_B Crystal Structure of Acetyl Xylan Esterase 1 from Thermoanaerobacterium sp. JW/SL YS485 [Thermoanaerobacterium saccharolyticum JW/SL-YS485],3FCY_C Crystal Structure of Acetyl Xylan Esterase 1 from Thermoanaerobacterium sp. JW/SL YS485 [Thermoanaerobacterium saccharolyticum JW/SL-YS485]
7CUZ_A	9.82e-77	8	319	4	310	ChainA, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147],7CUZ_B Chain B, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147],7CUZ_C Chain C, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147],7CUZ_D Chain D, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147]
6AGQ_A	2.02e-53	1	307	1	307	Acetylxylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_B Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_C Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_D Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_E Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_F Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4]
2XLB_A	7.13e-50	1	317	1	312	Acetylxylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_B Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_C Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_D Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_E Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_F Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_G Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_H Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_I Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_J Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_K Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_L Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus]
2XLC_A	7.75e-49	4	317	4	312	Acetylxylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_B Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_C Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_D Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_E Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_F Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P94388	1.12e-47	1	323	1	318	Cephalosporin-C deacetylase OS=Bacillus subtilis (strain 168) OX=224308 GN=cah PE=1 SV=1
Q9WXT2	6.64e-38	4	304	4	304	Cephalosporin-C deacetylase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=axeA PE=1 SV=1
D5EXI2	7.01e-17	3	317	128	434	Acetyl esterase Axe7A OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23) OX=264731 GN=axe7A PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000042	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004126_02186.