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CAZyme Information: MGYG000004167_00460

You are here: Home > Sequence: MGYG000004167_00460

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes; Bacilli; RF39; UBA660; CAG-884;
CAZyme ID MGYG000004167_00460
CAZy Family GT4
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
385 MGYG000004167_4|CGC1 44609.08 9.3901
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004167 1207995 MAG United Kingdom Europe
Gene Location Start: 54513;  End: 55670  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004167_00460.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT4 228 364 2.2e-16 0.925

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03825 GT4_WcaC-like 1.17e-89 62 385 22 362
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
cd03801 GT4_PimA-like 6.75e-24 12 360 13 328
phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
COG0438 RfaB 2.33e-20 13 366 15 343
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
PRK10125 PRK10125 4.86e-15 89 214 95 223
colanic acid biosynthesis glycosyltransferase WcaC.
cd03808 GT4_CapM-like 7.83e-15 192 362 152 326
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ANW97650.1 3.97e-125 3 385 2 397
QNO13419.1 1.15e-124 3 360 2 361
AEM72860.1 1.78e-122 4 366 11 377
ADQ41732.1 1.78e-122 4 366 11 377
CEP78286.1 4.99e-122 3 369 2 373

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P71237 3.60e-17 4 345 3 349
Putative colanic acid biosynthesis glycosyl transferase WcaC OS=Escherichia coli (strain K12) OX=83333 GN=wcaC PE=4 SV=2
D2B9F4 4.75e-06 204 342 206 362
D-inositol 3-phosphate glycosyltransferase OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) OX=479432 GN=mshA PE=3 SV=1
B2V5P9 8.88e-06 72 385 113 467
Glycogen synthase OS=Sulfurihydrogenibium sp. (strain YO3AOP1) OX=436114 GN=glgA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000052 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004167_00460.