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CAZyme Information: MGYG000004168_00752
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; Firm-11; | |||||||||||
| CAZyme ID | MGYG000004168_00752 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 102314; End: 106450 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 930 | 1174 | 4.2e-51 | 0.9147982062780269 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 1.57e-23 | 1184 | 1374 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 9.32e-18 | 934 | 1179 | 50 | 277 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 8.77e-14 | 927 | 1110 | 16 | 202 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| pfam13231 | PMT_2 | 1.77e-09 | 957 | 1108 | 2 | 131 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| COG5542 | COG5542 | 1.33e-08 | 298 | 431 | 92 | 220 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUC68008.1 | 1.56e-301 | 1 | 1378 | 1 | 1422 |
| QTE75201.1 | 5.93e-298 | 4 | 1378 | 4 | 1422 |
| QTE71236.1 | 1.06e-297 | 22 | 1378 | 8 | 1407 |
| QUA53848.1 | 5.49e-297 | 11 | 1368 | 17 | 1362 |
| QTE68569.1 | 2.08e-296 | 26 | 1368 | 35 | 1392 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 2.54e-21 | 923 | 1366 | 56 | 506 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 1.93e-20 | 934 | 1359 | 73 | 504 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 1.93e-20 | 934 | 1359 | 73 | 504 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 3.10e-10 | 957 | 1373 | 99 | 516 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000263 | 0.999004 | 0.000235 | 0.000172 | 0.000167 | 0.000157 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 7 | 29 |
| 215 | 232 |
| 245 | 264 |
| 301 | 320 |
| 327 | 349 |
| 359 | 378 |
| 385 | 404 |
| 419 | 436 |
| 449 | 471 |
| 486 | 508 |
| 515 | 537 |
| 552 | 571 |
| 576 | 598 |
| 602 | 619 |
| 645 | 664 |
| 684 | 706 |
| 749 | 771 |
| 977 | 999 |
| 1027 | 1049 |
| 1087 | 1109 |
| 1148 | 1170 |
| 1246 | 1268 |
| 1281 | 1300 |
| 1305 | 1327 |
| 1340 | 1362 |