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CAZyme Information: MGYG000004172_00061

You are here: Home > Sequence: MGYG000004172_00061

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; ;
CAZyme ID MGYG000004172_00061
CAZy Family PL6
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
752 MGYG000004172_1|CGC3 82155.06 6.5087
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004172 3050906 MAG United Kingdom Europe
Gene Location Start: 74109;  End: 76367  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL6 30 391 2e-123 0.967741935483871
PL6 444 655 7.6e-38 0.5994236311239193

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14251 PL-6 1.35e-163 28 389 3 364
Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.
pfam14592 Chondroitinas_B 2.33e-113 35 389 10 378
Chondroitinase B. This family includes chondroitinases. These enzymes cleave the glycosaminoglycan dermatan sulfate.
pfam13229 Beta_helix 1.83e-05 569 718 2 136
Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUT26279.1 0.0 22 752 24 753
QIU93442.1 0.0 22 750 24 751
QNL39961.1 0.0 22 752 24 753
QNT66846.1 7.12e-235 22 715 24 711
QRQ49286.1 2.21e-224 25 743 23 743

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7DMK_A 1.20e-225 27 744 15 734
ChainA, BcAlyPL6 [Bacteroides clarus],7DMK_B Chain B, BcAlyPL6 [Bacteroides clarus],7DMK_C Chain C, BcAlyPL6 [Bacteroides clarus],7DMK_D Chain D, BcAlyPL6 [Bacteroides clarus]
5GKD_A 3.65e-133 28 678 7 678
Structureof PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_B Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_C Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_D Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis]
5GKQ_A 2.83e-132 28 678 7 678
Structureof PL6 family alginate lyase AlyGC mutant-R241A [Paraglaciecola chathamensis S18K6],5GKQ_B Structure of PL6 family alginate lyase AlyGC mutant-R241A [Paraglaciecola chathamensis S18K6]
7O77_A 4.15e-121 35 678 13 678
ChainA, Poly(Beta-D-mannuronate) lyase [Pseudoalteromonas atlantica T6c]
7O7T_A 4.15e-121 35 678 13 678
ChainA, Poly(Beta-D-mannuronate) lyase [Pseudoalteromonas atlantica T6c]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q06365 4.94e-76 41 436 2 377
Alginate lyase OS=Pseudomonas sp. (strain OS-ALG-9) OX=86038 GN=aly PE=3 SV=1
Q46079 5.15e-23 30 338 32 349
Chondroitinase-B OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=cslB PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000302 0.998976 0.000241 0.000154 0.000153 0.000155

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004172_00061.