CAZyme Information: MGYG000004197_00807

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes_A
• CAZyme ID: MGYG000004197_00807
• CAZy Family: GH127
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
692		78013.51	5.0355

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004197	2419423	MAG	United Kingdom	Europe

• Gene Location: Start: 2533; End: 4611 Strand: +

Full Sequence      

MFFLKSLGCRFMFFDLSDLTFNLYAKFMMKKLVFCMAAACLMGVQVQAGSSGKKEQKKLP
VLVENKLNPAPYGATHFGGYLGNKIDLCIENRLMAQDIERIIQPFRDKPDGSWGFRSEFW
GKWYTAAMQGYAYAPTEENRAVVDRAVQELIATQDSAGYIGTYLTENHLGEWDIWGRKYV
MLGLLAYYDQTQDASVLDAACKVADNLIEEAGPESGVNIAATGWIGWKGLASSSVLEPIA
LLYQKTGNPRYLEFAEHIIKSWDTPNKLTPTGIRLVQEALSGTPLWKMSGAPKAYEMMSC
FEGLCEMYRITGNPLYFEACHKLINTIIRDEIMIVGSASMMEIWCHGKMRQTEPMYQGME
TCVTATWMKFLYQMLRLTGDSRYADQLETSLYNALLAAMAPKGEWWSYYSSLMGERVHSH
QQFPDVVMSCCVANGPRGLMTTPSWAVMTSSSGVTINLYGKMNSTVTTPVGQTLDLAMDT
EYPVQGAISTTLTLPESEKFAVALRIPEWSKETKVRINGEPYDGYLIPGTYASIERQWST
GDKIDIELDMRARVVEAPSGVGDAAIVRGPIVLAFDSRLIPRRDGVTEPPMYRYEFMGDE
EGYIDVQLVEQTDVPEIWMTFEVPCKDEAGGKHLMRMCDYVSAGNSWKEGNIFRVWTQQP
FDYRHLYTNNLDWRVNVTVGVGRPEVPDIYKK

Enzyme Prediction     

No EC number prediction in MGYG000004197_00807.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	115	573	6.6e-64	0.898854961832061

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	1.11e-68	113	574	53	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	2.69e-60	60	576	2	503	Uncharacterized conserved protein, DUF1680 family [Function unknown].
cd04791	LanC_SerThrkinase	2.81e-06	182	260	93	173	Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.
COG4225	YesR	6.10e-04	170	272	32	121	Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism].
cd04792	LanM-like	0.001	182	260	599	681	Cyclases involved in the biosynthesis of class II lantibiotics, and similar proteins. LanM-like proteins. LanM is a bifunctional enzyme, involved in the synthesis of class II lantibiotics. It is responsible for both the dehydration and the cyclization of the precursor-peptide during lantibiotic synthesis. The C-terminal domain shows similarity to LanC, the cyclase component of the lan operon, but the N terminus seems to be unrelated to the dehydratase, LanB.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ARE60508.1	3.47e-118	79	656	31	605
QWG10444.1	1.00e-45	79	606	47	614
AZQ63834.1	3.97e-44	79	598	47	610
QHS51661.1	1.05e-43	122	576	123	582
CAB9494536.1	2.96e-43	66	588	21	581

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MQO_A	1.35e-31	31	577	5	610	Glycosidehydrolase BT_1003 [Bacteroides thetaiotaomicron]
6EX6_A	1.01e-26	128	572	76	543	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
3WRE_A	2.36e-25	122	572	80	564	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	2.44e-25	122	572	80	564	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]
7EXU_A	5.70e-25	122	572	80	564	ChainA, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	1.29e-24	122	572	80	564	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.465427	0.429802	0.103276	0.000544	0.000432	0.000516

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004197_00807.