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CAZyme Information: MGYG000004199_00919

You are here: Home > Sequence: MGYG000004199_00919

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes; Bacilli; RFN20; CAG-449; CAG-449;
CAZyme ID MGYG000004199_00919
CAZy Family GH18
CAZyme Description Spore germination protein YaaH
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
421 MGYG000004199_17|CGC1 48224.77 7.5378
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004199 1652569 MAG United Kingdom Europe
Gene Location Start: 155;  End: 1420  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004199_00919.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 123 404 3.7e-34 0.8344594594594594

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 2.68e-101 107 403 5 303
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 3.43e-96 1 417 1 422
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
smart00636 Glyco_18 3.29e-24 120 404 20 333
Glyco_18 domain.
cd06549 GH18_trifunctional 1.99e-20 160 400 60 288
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.
cd02876 GH18_SI-CLP 4.16e-20 173 412 77 317
Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QCX33332.1 1.89e-101 1 415 1 418
APC38872.1 1.51e-100 1 417 1 420
CDZ24826.1 2.14e-100 4 402 4 405
QNU67347.1 4.14e-100 4 417 4 420
QNK40400.1 8.53e-100 1 417 1 420

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4S3K_A 2.97e-63 6 417 9 427
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
4S3J_A 9.92e-59 6 419 8 427
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
3CZ8_A 6.25e-53 112 403 19 309
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4Q6T_A 4.60e-22 168 400 77 322
Thecrystal structure of a class V chitininase from Pseudomonas fluorescens Pf-5 [Pseudomonas protegens Pf-5]
5JH8_A 7.53e-20 165 402 67 299
Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P37531 1.54e-61 4 417 4 423
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
P0DPJ9 3.61e-58 6 419 7 426
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
Q9K3E4 9.93e-58 6 419 7 426
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1
O05495 3.20e-56 1 403 1 401
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
O32258 1.28e-24 92 402 16 328
Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999559 0.000463 0.000009 0.000001 0.000000 0.000001

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004199_00919.