CAZyme Information: MGYG000004203_01914

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Acetatifactor
• CAZyme ID: MGYG000004203_01914
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
636	MGYG000004203_17|CGC2	71908.36	5.582

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004203	2860639	MAG	United Kingdom	Europe

• Gene Location: Start: 62889; End: 64799 Strand: +

Full Sequence      

MNLRSLVKQLLIQKENKRYAGKLAARQVSYEKWVDRLDHSDGWEAAERSDKEPRSFQCYV
AADGVVAEGAFTRIERYFREHPQVKVVYGDEDVLENGVRKSPWFKPDWSPDLFQSFFYFG
SIVAVKNELAEQVPGEPGPDWVYDCVKLVGGYERGCSSIGHLPVILFHSSSEKQQQKYRQ
IQGRDSGLQCRASEQQDSPLTSQSGQPMYPEAQGNVREASVSIVIPSKDNPQVLRKCLEA
CMADAPGAEIIIVDNGSSPENKDCIRRMIEGKNIQYLYNPMPFNFSKMCNLGASAAKGEC
LLFLNDDVELCEPGTIARMAELATKSYVGAVGMKLYYPDSDKIQHAGITNLPMGPVHKMQ
FLPDREEYYFGSNRGMRDVLAVTAACLMVQRNKFKEAGGFAEELAVAFNDVDFCFTLHEK
GYWNVCLNDSHAFHHESLSRGDDEAPEKLGRLLAERDRLYRRHPALEGKDPFYSPYLNRE
GLDTRIRPAYETAGNEMQRQEKELSEIHLESYRNDPCVLLRIESFQNGILQGYSVVLGDN
NACYDKKILLIPEAETAGTYAIPLEGQYRPDLVENMPDQTNVGLSGFWMMLSDEALDKIP
AGRYRIGEAVKNRVTGLRLMNKSNRYLIVLHNGDRT

Enzyme Prediction     

No EC number prediction in MGYG000004203_01914.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	222	377	4e-20	0.9470588235294117

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04186	GT_2_like_c	3.57e-30	223	436	1	166	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1216	GT2	2.37e-26	218	466	2	253	Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
cd04184	GT2_RfbC_Mx_like	4.66e-18	59	168	86	199	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
pfam00535	Glycos_transf_2	7.31e-18	222	377	1	160	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd00761	Glyco_tranf_GTA_type	5.14e-15	223	336	1	119	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNM02107.1	2.73e-169	1	627	1	665
AOZ95571.1	6.06e-115	43	621	77	693
ADL33298.1	5.21e-113	3	621	2	694
CBK92935.1	3.93e-88	56	629	143	709
QWT52131.1	1.52e-87	59	606	484	1034

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P55465	2.52e-50	63	483	458	894	Uncharacterized protein y4gI OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) OX=394 GN=NGR_a03550 PE=4 SV=1
Q50864	6.08e-47	56	487	404	841	O-antigen biosynthesis protein RfbC OS=Myxococcus xanthus OX=34 GN=rfbC PE=4 SV=1
P9WMY2	7.15e-06	223	445	8	246	N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=wbbL PE=3 SV=2
P9WMY3	7.15e-06	223	445	8	246	N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=wbbL PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000029	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004203_01914.